Dopa Decarboxylase (DDC) ELISA Kit for Human

Name: Human DDC ELISA Kit; Dopa Decarboxylase; MyBioSource
Brand: MyBioSource
SKU: MBS458805
Price: 540 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458805

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to DDC. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to DDC. Next,… More details

$540 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Dopa Decarboxylase (DDC), ELISA Kit

Full Product Name

Human Dopa Decarboxylase (DDC) ELISA Kit

Product Gene Name

DDC elisa kit

Product Synonym Names

AADC; Aromatic L-Amino Acid Decarboxylase; DOPA decarboxylase

Species Reactivity

Human

Assay Type

Sandwich

Samples

Tissue Homogenates, Cell Lysates or Other Biological Fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.068ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

44,239 Da

OMIM

107930

3D Structure

ModBase 3D Structure for P20711

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of DDC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DDC purchase

MBS458805 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Dopa Decarboxylase (DDC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DDC. The ELISA analytical biochemical technique of the MBS458805 kit is based on DDC antibody-DDC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DDC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DDC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for DDC. It may not necessarily be applicable to this product.

NCBI GI #

4503281

NCBI GeneID

1644

NCBI Accession #

NP_000781.1

UniProt Primary Accession #

P20711

UniProt Secondary Accession #

Q16723; Q5W5T9; Q75MJ6; C9IYA0; E7ER62; E7EU95

UniProt Related Accession #

P20711

GenBank Nucleotide #

NM_000790.3

NCBI Official Full Name

aromatic-L-amino-acid decarboxylase isoform 1

NCBI Official Synonym Full Names

dopa decarboxylase

NCBI Official Symbol

DDC

NCBI Official Synonym Symbols

AADC

UniProt Protein Name

Aromatic-L-amino-acid decarboxylase

UniProt Synonym Protein Names

DOPA decarboxylase; DDC

Protein Family

Aromatic-L-amino-acid decarboxylase

UniProt Gene Name

DDC

UniProt Synonym Gene Names

AADC; AADC; DDC

NCBI Protein Information

aromatic-L-amino-acid decarboxylase

NCBI Summary for DDC

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]

UniProt Comments for DDC

Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.

Research Articles on DDC

1. IKZF1 rs10235796 C allele, IKZF1 rs6964969A>G, CDKN2A rs3731246 G>C, and CDKN2A rs3731246 C allele were signi fi cantly associated with Acute Lymphoblastic Leukemia in Yemenis of Arab-Asian descent. Borderline association found in IKZF1 rs4132601 T>G variant. No associations found with IKZF1 rs11978267 or rs7789635, DDC rs3779084; rs880028; rs7809758, CDKN2A rs3731217, CEBPE rs2239633; rs12434881

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DDC elisa kit

Reference Product	PubMed Publications
DBH elisa kit	>35 publications with DDC and DBH
COMT elisa kit	>31 publications with DDC and COMT
TPH2 elisa kit	>9 publications with DDC and TPH2
MAOA elisa kit	>8 publications with DDC and MAOA
TPH1 elisa kit	>6 publications with DDC and TPH1
TYR elisa kit	>5 publications with DDC and TYR
PAH elisa kit	>5 publications with DDC and PAH
MAOB elisa kit	>5 publications with DDC and MAOB
ABP1 elisa kit	>1 publications with DDC and ABP1

Pathways associated with DDC elisa kit

Products by Pathway	Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Amine-derived Hormones Pathway antibodies	Amine-derived Hormones Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Biogenic Amine Synthesis Pathway antibodies	Biogenic Amine Synthesis Pathway Diagram
Catecholamine Biosynthesis Pathway antibodies	Catecholamine Biosynthesis Pathway Diagram
Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway antibodies	Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway Diagram
Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway antibodies	Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway Diagram
Cocaine Addiction Pathway antibodies	Cocaine Addiction Pathway Diagram

Diseases associated with DDC elisa kit

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>116 publications with DDC and Disease Models, Animal
Liver Diseases Antibodies	>115 publications with DDC and Liver Diseases
Brain Diseases Antibodies	>93 publications with DDC and Brain Diseases
Poisoning Antibodies	>59 publications with DDC and Poisoning
Mental Disorders Antibodies	>58 publications with DDC and Mental Disorders
Movement Disorders Antibodies	>56 publications with DDC and Movement Disorders
Parkinsonian Disorders Antibodies	>52 publications with DDC and Parkinsonian Disorders
Necrosis Antibodies	>42 publications with DDC and Necrosis
Parkinson Disease Antibodies	>39 publications with DDC and Parkinson Disease
Inflammation Antibodies	>37 publications with DDC and Inflammation

Organs/Tissues associated with DDC elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>408 publications with DDC and Blood
Liver Antibodies	>309 publications with DDC and Liver
Brain Antibodies	>267 publications with DDC and Brain
Nerve Antibodies	>71 publications with DDC and Nerve
Kidney Antibodies	>66 publications with DDC and Kidney
Lung Antibodies	>46 publications with DDC and Lung
Eye Antibodies	>29 publications with DDC and Eye
Intestine Antibodies	>28 publications with DDC and Intestine
Prostate Antibodies	>24 publications with DDC and Prostate
Pancreas Antibodies	>19 publications with DDC and Pancreas