Discs, Large Homolog 4 (DLG4) ELISA Kit for Mouse

Name: Mouse DLG4 ELISA Kit; Discs, Large Homolog 4; MyBioSource
Brand: MyBioSource
SKU: MBS458871
Price: 550 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458871

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to DLG4. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to DLG4.… More details

$550 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Discs, Large Homolog 4 (DLG4), ELISA Kit

Full Product Name

Mouse Discs, Large Homolog 4 (DLG4) ELISA Kit

Product Gene Name

DLG4 elisa kit

Product Synonym Names

PSD95; SAP90; Postsynaptic density protein 95; Synapse-associated protein 90

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Tissue Homogenates, Cell Lysates or Other Biological Fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.059ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

80,102 Da

3D Structure

ModBase 3D Structure for Q62108

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of DLG4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLG4 purchase

MBS458871 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Discs, Large Homolog 4 (DLG4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DLG4. The ELISA analytical biochemical technique of the MBS458871 kit is based on DLG4 antibody-DLG4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DLG4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DLG4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for DLG4. It may not necessarily be applicable to this product.

NCBI GI #

157909820

NCBI GeneID

13385

NCBI Accession #

NP_001103222.1

UniProt Primary Accession #

Q62108

UniProt Secondary Accession #

Q5NCV5; Q5NCV6; Q5NCV7; Q91WJ1

UniProt Related Accession #

Q62108

GenBank Nucleotide #

NM_001109752.1

NCBI Official Full Name

disks large homolog 4 isoform 2

NCBI Official Synonym Full Names

discs large MAGUK scaffold protein 4

NCBI Official Symbol

Dlg4

NCBI Official Synonym Symbols

Dlgh4; PSD95; SAP90; PSD-95; SAP90A

UniProt Protein Name

Disks large homolog 4

UniProt Synonym Protein Names

Postsynaptic density protein 95; PSD-95; Synapse-associated protein 90; SAP-90; SAP90

Protein Family

Disks large

UniProt Gene Name

Dlg4

UniProt Synonym Gene Names

Dlgh4; Psd95; PSD-95; SAP-90; SAP90

NCBI Protein Information

disks large homolog 4

UniProt Comments for DLG4

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (Probable).

Research Articles on DLG4

1. Results show the binding of PSD95 to GluN subunit 2A is modulated by CIN.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DLG4 elisa kit

Reference Product	PubMed Publications
Grin2b elisa kit	>4 publications with DLG4 and Grin2b
Grin1 elisa kit	>3 publications with DLG4 and Grin1
Grin2a elisa kit	>3 publications with DLG4 and Grin2a
Grin2c elisa kit	>1 publications with DLG4 and Grin2c
Cacng2 elisa kit	>1 publications with DLG4 and Cacng2
Grin2d elisa kit	>1 publications with DLG4 and Grin2d
Gria1 elisa kit	>1 publications with DLG4 and Gria1

Pathways associated with DLG4 elisa kit

Products by Pathway	Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
Activation Of Ca-permeable Kainate Receptor Pathway antibodies	Activation Of Ca-permeable Kainate Receptor Pathway Diagram
Activation Of Kainate Receptors Upon Glutamate Binding Pathway antibodies	Activation Of Kainate Receptors Upon Glutamate Binding Pathway Diagram
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies	Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
CREB Phosphorylation Through The Activation Of CaMKII Pathway antibodies	CREB Phosphorylation Through The Activation Of CaMKII Pathway Diagram
CREB Phosphorylation Through The Activation Of Ras Pathway antibodies	CREB Phosphorylation Through The Activation Of Ras Pathway Diagram
Cocaine Addiction Pathway antibodies	Cocaine Addiction Pathway Diagram
Cocaine Addiction Pathway antibodies	Cocaine Addiction Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram

Diseases associated with DLG4 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>46 publications with DLG4 and Nervous System Diseases
Brain Diseases Antibodies	>38 publications with DLG4 and Brain Diseases
Neurobehavioral Manifestations Antibodies	>9 publications with DLG4 and Neurobehavioral Manifestations
Disease Models, Animal Antibodies	>9 publications with DLG4 and Disease Models, Animal
Cognition Disorders Antibodies	>7 publications with DLG4 and Cognition Disorders
Movement Disorders Antibodies	>7 publications with DLG4 and Movement Disorders
Learning Disorders Antibodies	>5 publications with DLG4 and Learning Disorders
Pain Antibodies	>5 publications with DLG4 and Pain
Autism Spectrum Disorder Antibodies	>4 publications with DLG4 and Autism Spectrum Disorder
Inflammation Antibodies	>3 publications with DLG4 and Inflammation

Organs/Tissues associated with DLG4 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>120 publications with DLG4 and Brain
Embryonic Tissue Antibodies	>4 publications with DLG4 and Embryonic Tissue
Eye Antibodies	>4 publications with DLG4 and Eye
Lung Antibodies	>1 publications with DLG4 and Lung