Desmocollin 1 (DSC1) ELISA Kit for Mouse

Name: Mouse DSC1 ELISA Kit; Desmocollin 1; MyBioSource
Brand: MyBioSource
SKU: MBS458930
Price: 550 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458930

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to DSC1. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to DSC1.… More details

$550 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Desmocollin 1 (DSC1), ELISA Kit

Full Product Name

Mouse Desmocollin 1 (DSC1) ELISA Kit

Product Gene Name

DSC1 elisa kit

Product Synonym Names

CDHF1; DG2/DG3; Cadherin family member 1; Desmosomal glycoprotein 2/3

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Tissue Homogenates, Cell Lysates or Other Biological Fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.051ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

93,647 Da

3D Structure

ModBase 3D Structure for P55849

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of DSC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DSC1 purchase

MBS458930 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Desmocollin 1 (DSC1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DSC1. The ELISA analytical biochemical technique of the MBS458930 kit is based on DSC1 antibody-DSC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DSC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DSC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for DSC1. It may not necessarily be applicable to this product.

NCBI GI #

620597332

NCBI GeneID

13505

NCBI Accession #

NP_001278733.1

UniProt Primary Accession #

P55849

UniProt Secondary Accession #

E9QJX2

UniProt Related Accession #

P55849

GenBank Nucleotide #

NM_001291804.1

NCBI Official Full Name

desmocollin-1 isoform 1 preproprotein

NCBI Official Synonym Full Names

desmocollin 1

NCBI Official Symbol

Dsc1

NCBI Official Synonym Symbols

AI507491; 1110020A10Rik

UniProt Protein Name

Desmocollin-1

Protein Family

Desmocollin

UniProt Gene Name

Dsc1

NCBI Protein Information

desmocollin-1

NCBI Summary for DSC1

This gene encodes a member of the cadherin family of proteins that mediates adhesion in desmosomes. The encoded preproprotein undergoes proteolytic processing to generate the mature, functional protein. Mice lacking the encoded protein exhibit epidermal fragility together with defects of epidermal barrier and differentiation. The neonatal mice lacking the encoded protein exhibit epidermal lesions and older mice develop chronic dermatitis. This gene is located in a cluster of desmosomal cadherin genes on chromosome 18. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]

UniProt Comments for DSC1

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DSC1 elisa kit

Reference Product	PubMed Publications
Jup elisa kit	>4 publications with DSC1 and Jup
Pkp1 elisa kit	>2 publications with DSC1 and Pkp1
Pkp3 elisa kit	>2 publications with DSC1 and Pkp3
Cdx1 elisa kit	>1 publications with DSC1 and Cdx1

Pathways associated with DSC1 elisa kit

Products by Pathway	Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
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Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Keratinization Pathway antibodies	Keratinization Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram
XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies	XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram

Diseases associated with DSC1 elisa kit

Disease Name	Pubmed Publications
Respiratory Tract Diseases Antibodies	>2 publications with DSC1 and Respiratory Tract Diseases
Lung Neoplasms Antibodies	>2 publications with DSC1 and Lung Neoplasms
Lung Diseases Antibodies	>2 publications with DSC1 and Lung Diseases
Liver Diseases Antibodies	>2 publications with DSC1 and Liver Diseases
Melanoma Antibodies	>2 publications with DSC1 and Melanoma
Diabetes Mellitus Antibodies	>1 publications with DSC1 and Diabetes Mellitus
Cardiovascular Diseases Antibodies	>1 publications with DSC1 and Cardiovascular Diseases
Brain Diseases Antibodies	>1 publications with DSC1 and Brain Diseases
Fibrosis Antibodies	>1 publications with DSC1 and Fibrosis
Inflammation Antibodies	>1 publications with DSC1 and Inflammation

Organs/Tissues associated with DSC1 elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>66 publications with DSC1 and Skin
Embryonic Tissue Antibodies	>5 publications with DSC1 and Embryonic Tissue
Vagina Antibodies	>1 publications with DSC1 and Vagina