Delta-Sleep Inducing (dSIP) ELISA Kit for Human

Name: Human dSIP ELISA Kit; Delta-Sleep Inducing; MyBioSource
Brand: MyBioSource
SKU: MBS458937
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458937

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to dSIP. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to dSIP.… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Delta-Sleep Inducing Peptide (dSIP), ELISA Kit

Full Product Name

Human Delta-Sleep Inducing Peptide (dSIP) ELISA Kit

Product Gene Name

dSIP elisa kit

Product Synonym Names

DSIPI; TSC22D3; DIP; GILZ; TSC-22R; hDIP; TSC22 Domain Family Protein 3; Glucocorticoid-Induced Leucine Zipper; Delta Sleep Inducing Peptide,Immunoreactor

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates or Other Biological Fluids.

Detection Range

125-8000pg/mL

Sensitivity

47pg/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

13,286 Da

OMIM

300506

3D Structure

ModBase 3D Structure for Q99576

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of dSIP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for dSIP purchase

MBS458937 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Delta-Sleep Inducing Peptide (dSIP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing dSIP. The ELISA analytical biochemical technique of the MBS458937 kit is based on dSIP antibody-dSIP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect dSIP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, dSIP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for dSIP. It may not necessarily be applicable to this product.

NCBI GI #

62865625

NCBI GeneID

1831

NCBI Accession #

NP_001015881.1

UniProt Primary Accession #

Q99576

UniProt Secondary Accession #

Q5H9S3; Q5JRI9; Q6FIH6; Q8NAI1; Q8WVB9; Q9UBN5; Q9UG13

UniProt Related Accession #

Q99576

GenBank Nucleotide #

NM_001015881.1

NCBI Official Full Name

TSC22 domain family protein 3 isoform 3

NCBI Official Synonym Full Names

TSC22 domain family member 3

NCBI Official Symbol

TSC22D3

NCBI Official Synonym Symbols

DIP; GILZ; DSIPI; TSC-22R

UniProt Protein Name

TSC22 domain family protein 3

UniProt Synonym Protein Names

DSIP-immunoreactive peptide; Protein DIP; hDIP; Delta sleep-inducing peptide immunoreactor; Glucocorticoid-induced leucine zipper protein; GILZ; TSC-22-like protein; TSC-22-related protein; TSC-22R

Protein Family

Delta sleep-inducing peptide

UniProt Gene Name

TSC22D3

UniProt Synonym Gene Names

DSIPI; GILZ; Protein DIP; hDIP; GILZ; TSC-22R

NCBI Protein Information

TSC22 domain family protein 3

NCBI Summary for dSIP

This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

UniProt Comments for dSIP

Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (). Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG ().

Research Articles on dSIP

1. The mRNA expression of GILZ was significantly correlated with Systemic Lupus Erythematosus Disease Activity Index score.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with dSIP elisa kit

Reference Product	PubMed Publications
JUN elisa kit	>10 publications with dSIP and JUN
SGK1 elisa kit	>8 publications with dSIP and SGK1
CD86 elisa kit	>2 publications with dSIP and CD86
CCND1 elisa kit	>2 publications with dSIP and CCND1
FOS elisa kit	>2 publications with dSIP and FOS
PTGS2 elisa kit	>1 publications with dSIP and PTGS2
IL2 elisa kit	>1 publications with dSIP and IL2

Pathways associated with dSIP elisa kit

Products by Pathway	Pathway Diagram
Ion Channel Transport Pathway antibodies	Ion Channel Transport Pathway Diagram
Stimuli-sensing Channels Pathway antibodies	Stimuli-sensing Channels Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with dSIP elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>20 publications with dSIP and Inflammation
Necrosis Antibodies	>6 publications with dSIP and Necrosis
Lung Diseases Antibodies	>5 publications with dSIP and Lung Diseases
Nervous System Diseases Antibodies	>4 publications with dSIP and Nervous System Diseases
Cardiovascular Diseases Antibodies	>3 publications with dSIP and Cardiovascular Diseases
Depressive Disorder Antibodies	>3 publications with dSIP and Depressive Disorder
Liver Diseases Antibodies	>3 publications with dSIP and Liver Diseases
Neoplasms, Experimental Antibodies	>2 publications with dSIP and Neoplasms, Experimental
Ovarian Neoplasms Antibodies	>2 publications with dSIP and Ovarian Neoplasms
Carcinoma Antibodies	>2 publications with dSIP and Carcinoma

Organs/Tissues associated with dSIP elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>29 publications with dSIP and Blood
Lung Antibodies	>7 publications with dSIP and Lung
Kidney Antibodies	>6 publications with dSIP and Kidney
Brain Antibodies	>6 publications with dSIP and Brain
Liver Antibodies	>5 publications with dSIP and Liver
Bone Antibodies	>4 publications with dSIP and Bone
Muscle Antibodies	>3 publications with dSIP and Muscle
Vascular Antibodies	>3 publications with dSIP and Vascular
Ovary Antibodies	>3 publications with dSIP and Ovary
Nerve Antibodies	>3 publications with dSIP and Nerve