Ephrin A4 (EFNA4) ELISA Kit for Human

Name: Human EFNA4 ELISA Kit; Ephrin A4; MyBioSource
Brand: MyBioSource
SKU: MBS458999
Price: 540 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458999

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to EFNA4. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to EFNA4.… More details

$540 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Ephrin A4 (EFNA4), ELISA Kit

Full Product Name

Human Ephrin A4 (EFNA4) ELISA Kit

Product Gene Name

EFNA4 elisa kit

Product Synonym Names

EFL4; EPLG4; LERK4; EPH-related receptor tyrosine kinase ligand 4

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates, Cell Lysates or Other Biological Fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.117ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

22,584 Da

OMIM

601380

3D Structure

ModBase 3D Structure for P52798

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of EFNA4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EFNA4 purchase

MBS458999 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ephrin A4 (EFNA4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EFNA4. The ELISA analytical biochemical technique of the MBS458999 kit is based on EFNA4 antibody-EFNA4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EFNA4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EFNA4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for EFNA4. It may not necessarily be applicable to this product.

NCBI GI #

4885197

NCBI GeneID

1945

NCBI Accession #

NP_005218.1

UniProt Primary Accession #

P52798

UniProt Secondary Accession #

O95457; Q5SR71; Q6FI57; C9JHJ8; G3XAK2

UniProt Related Accession #

P52798

GenBank Nucleotide #

NM_005227.2

NCBI Official Full Name

ephrin-A4 isoform a

NCBI Official Synonym Full Names

ephrin A4

NCBI Official Symbol

EFNA4

NCBI Official Synonym Symbols

EFL4; EPLG4; LERK4

UniProt Protein Name

Ephrin-A4

UniProt Synonym Protein Names

EPH-related receptor tyrosine kinase ligand 4; LERK-4

Protein Family

Ephrin

UniProt Gene Name

EFNA4

UniProt Synonym Gene Names

EPLG4; LERK4; LERK-4

NCBI Protein Information

ephrin-A4

NCBI Summary for EFNA4

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified. [provided by RefSeq, Jul 2008]

UniProt Comments for EFNA4

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.

Research Articles on EFNA4

1. Study present for the first time in vitro and in vivo evidence suggesting that the major role of two ephrin A4 isoforms in chronic lymphocytic leukemia could be related with a non-previously described mechanism of survival linked to extravasation strongly dependent on integrin signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EFNA4 elisa kit

Reference Product	PubMed Publications
EPHA2 elisa kit	>2 publications with EFNA4 and EPHA2
EPHA4 elisa kit	>1 publications with EFNA4 and EPHA4

Pathways associated with EFNA4 elisa kit

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Diseases associated with EFNA4 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with EFNA4 and Neoplasms
Immune System Diseases Antibodies	>3 publications with EFNA4 and Immune System Diseases
Bone Diseases Antibodies	>2 publications with EFNA4 and Bone Diseases
Nervous System Diseases Antibodies	>1 publications with EFNA4 and Nervous System Diseases
Chromosome Aberrations Antibodies	>1 publications with EFNA4 and Chromosome Aberrations
Necrosis Antibodies	>1 publications with EFNA4 and Necrosis