Family with Sequence Similarity 5, Member C (FAM5C) ELISA Kit for Human

Name: Human FAM5C ELISA Kit; Family with Sequence Similarity 5, Member C; MyBioSource
Brand: MyBioSource
SKU: MBS459191
Price: 575 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS459191

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to FAM5C. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to FAM5C.… More details

$575 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Family With Sequence Similarity 5, Member C (FAM5C), ELISA Kit

Full Product Name

Human Family With Sequence Similarity 5, Member C (FAM5C) ELISA Kit

Product Gene Name

FAM5C elisa kit

Product Synonym Names

DBCCR1L; DBCCR1L1; DBCCR1-like protein 1; BMP/retinoic acid-inducible neural-specific protein 3

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates or Other Biological Fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.113ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

76,299 Da

3D Structure

ModBase 3D Structure for Q76B58

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of FAM5C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FAM5C purchase

MBS459191 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Family With Sequence Similarity 5, Member C (FAM5C) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FAM5C. The ELISA analytical biochemical technique of the MBS459191 kit is based on FAM5C antibody-FAM5C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FAM5C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FAM5C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FAM5C. It may not necessarily be applicable to this product.

NCBI GI #

953953831

NCBI GeneID

339479

NCBI Accession #

NP_001304117.1

UniProt Primary Accession #

Q76B58

UniProt Secondary Accession #

O95726; Q2M330; B3KVP1; B7Z260

UniProt Related Accession #

Q76B58

GenBank Nucleotide #

NM_001317188.1

NCBI Official Full Name

BMP/retinoic acid-inducible neural-specific protein 3 isoform 2

NCBI Official Synonym Full Names

BMP/retinoic acid inducible neural specific 3

NCBI Official Symbol

BRINP3

NCBI Official Synonym Symbols

FAM5C; DBCCR1L; DBCCR1L1

UniProt Protein Name

BMP/retinoic acid-inducible neural-specific protein 3

UniProt Synonym Protein Names

DBCCR1-like protein 1

UniProt Gene Name

BRINP3

UniProt Synonym Gene Names

DBCCR1L; DBCCR1L1; FAM5C

NCBI Protein Information

BMP/retinoic acid-inducible neural-specific protein 3

NCBI Summary for FAM5C

This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

UniProt Comments for FAM5C

Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.

Research Articles on FAM5C

1. the association of serum OGN and FAM5C levels and muscle mass with bone mineral density (BMD), bone turnover markers, and the presence of vertebral fractures (VFs) in 156 postmenopausal women with type 2 diabetes mellitus, is reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FAM5C elisa kit

Reference Product	PubMed Publications
FAM5C elisa kit	>2 publications with FAM5C and FAM5C

Diseases associated with FAM5C elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>2 publications with FAM5C and Inflammation
Learning Disorders Antibodies	>1 publications with FAM5C and Learning Disorders
Anxiety Disorders Antibodies	>1 publications with FAM5C and Anxiety Disorders

Organs/Tissues associated with FAM5C elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with FAM5C and Brain
Intestine Antibodies	>1 publications with FAM5C and Intestine