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Fatty Acid Synthase (FASN) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS459203

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to FASN. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to FASN.… More details

$540 / 48 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fatty Acid Synthase (FASN), ELISA Kit
Full Product Name
Human Fatty Acid Synthase (FASN) ELISA Kit
Product Gene Name
FASN elisa kit
Product Synonym Names
FAS; OA519; SDR27X1; Short Chain Dehydrogenase/Reductase Family 27X,Member 1; S-acetyltransferase; 3-oxoacyl synthase; Oleoyl hydrolase; Enoyl-acyl-carrier-protein reductase
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, Plasma, Tissue Homogenates or Other Biological Fluids.
Detection Range
0.312-20ng/mL
Sensitivity
0.124ng/mL
Preparation and Storage
For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.
Molecular Weight
273,427 Da
OMIM
600212
3D Structure
ModBase 3D Structure for P49327
RTU ELISA Kit's Advantage
The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of FASN elisa kit

Human FASN ELISA Kit – Cat# MBS459203

Other Notes

Small volumes of FASN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FASN purchase

MBS459203 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fatty Acid Synthase (FASN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FASN. The ELISA analytical biochemical technique of the MBS459203 kit is based on FASN antibody-FASN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FASN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FASN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FASN. It may not necessarily be applicable to this product.

NCBI GI #
41872631
NCBI GeneID
2194
NCBI Accession #
NP_004095.4
UniProt Primary Accession #
P49327
UniProt Secondary Accession #
Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0
UniProt Related Accession #
P49327
GenBank Nucleotide #
NM_004104.4
NCBI Official Full Name
fatty acid synthase
NCBI Official Synonym Full Names
fatty acid synthase
NCBI Official Symbol
FASN
NCBI Official Synonym Symbols
FAS; OA-519; SDR27X1
UniProt Protein Name
Fatty acid synthase
Protein Family
Fatty acid synthase
UniProt Gene Name
FASN
UniProt Synonym Gene Names
FAS
NCBI Protein Information
fatty acid synthase

NCBI Summary for FASN

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
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UniProt Comments for FASN

Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.

Research Articles on FASN

1. Fatty acid synthase (FASN) mRNA and protein overexpression were associated with unfavorable clinicopathologic factors and poor outcomes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FASN elisa kit

 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Activation Of Gene Expression By SREBP (SREBF) Pathway antibodies  Activation Of Gene Expression By SREBP (SREBF) Pathway Diagram
 ChREBP Activates Metabolic Gene Expression Pathway antibodies  ChREBP Activates Metabolic Gene Expression Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Fatty Acyl-CoA Biosynthesis Pathway antibodies  Fatty Acyl-CoA Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation Pathway antibodies  Fatty Acid Biosynthesis, Elongation Pathway Diagram
 Fatty Acid Biosynthesis, Elongation Pathway antibodies  Fatty Acid Biosynthesis, Elongation Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram

Diseases associated with FASN elisa kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >158 publications with FASN and Neoplasms
 Fatty Liver Antibodies  >81 publications with FASN and Fatty Liver
 Obesity Antibodies  >69 publications with FASN and Obesity
 Liver Diseases Antibodies  >36 publications with FASN and Liver Diseases
 Breast Neoplasms Antibodies  >36 publications with FASN and Breast Neoplasms
 Insulin Resistance Antibodies  >31 publications with FASN and Insulin Resistance
 Inflammation Antibodies  >25 publications with FASN and Inflammation
 Weight Loss Antibodies  >16 publications with FASN and Weight Loss
 Drug Toxicity Antibodies  >15 publications with FASN and Drug Toxicity
 Hepatitis Antibodies  >12 publications with FASN and Hepatitis

Organs/Tissues associated with FASN elisa kit

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >98 publications with FASN and Liver
 Adipose Tissue Antibodies  >73 publications with FASN and Adipose Tissue
 Blood Antibodies  >72 publications with FASN and Blood
 Connective Tissue Antibodies  >45 publications with FASN and Connective Tissue
 Muscle Antibodies  >34 publications with FASN and Muscle
 Prostate Antibodies  >34 publications with FASN and Prostate
 Mammary Gland Antibodies  >21 publications with FASN and Mammary Gland
 Lung Antibodies  >13 publications with FASN and Lung
 Brain Antibodies  >12 publications with FASN and Brain
 Kidney Antibodies  >10 publications with FASN and Kidney
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