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Fibulin 4 (FBLN4) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS459222

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to FBLN4. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to FBLN4.… More details

$540 / 48 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fibulin 4 (FBLN4), ELISA Kit
Full Product Name
Human Fibulin 4 (FBLN4) ELISA Kit
Product Gene Name
FBLN4 elisa kit
Product Synonym Names
EFEMP2; MBP1; UPH1; EGF-Containing Fibulin-Like Extracellular Matrix Protein 2
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, Plasma, Tissue Homogenates or Other Biological Fluids.
Detection Range
3.12-200ng/mL
Sensitivity
1.48ng/mL
Preparation and Storage
For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.
Molecular Weight
49,405 Da
OMIM
604633
3D Structure
ModBase 3D Structure for O95967
RTU ELISA Kit's Advantage
The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of FBLN4 elisa kit

Human FBLN4 ELISA Kit – Cat# MBS459222

Other Notes

Small volumes of FBLN4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FBLN4 purchase

MBS459222 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fibulin 4 (FBLN4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FBLN4. The ELISA analytical biochemical technique of the MBS459222 kit is based on FBLN4 antibody-FBLN4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FBLN4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FBLN4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FBLN4. It may not necessarily be applicable to this product.

NCBI GI #
320118911
NCBI GeneID
30008
NCBI Accession #
NP_058634.4
UniProt Primary Accession #
O95967
UniProt Secondary Accession #
O75967; A8K7R4; B3KM31; B3KQT1
UniProt Related Accession #
O95967
GenBank Nucleotide #
NM_016938.4
NCBI Official Full Name
EGF-containing fibulin-like extracellular matrix protein 2
NCBI Official Synonym Full Names
EGF containing fibulin extracellular matrix protein 2
NCBI Official Symbol
EFEMP2
NCBI Official Synonym Symbols
MBP1; UPH1; FBLN4; ARCL1B
UniProt Protein Name
EGF-containing fibulin-like extracellular matrix protein 2
UniProt Synonym Protein Names
Fibulin-4; FIBL-4; Protein UPH1
UniProt Gene Name
EFEMP2
UniProt Synonym Gene Names
FBLN4; FIBL-4
NCBI Protein Information
EGF-containing fibulin-like extracellular matrix protein 2

NCBI Summary for FBLN4

A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011]
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Research Articles on FBLN4

1. different mutations in the fibulin-4 gene result in different molecular defects affecting secretion rates, protein stability, LOX-induced cross-linking, or binding to other ECM components and molecules of the TGF-beta pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FBLN4 elisa kit

 Reference Product  PubMed Publications
 AQP1 elisa kit  >1 publications with FBLN4 and AQP1

Pathways associated with FBLN4 elisa kit

 Products by Pathway  Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Molecules Associated With Elastic Fibres Pathway antibodies  Molecules Associated With Elastic Fibres Pathway Diagram

Diseases associated with FBLN4 elisa kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with FBLN4 and Neoplasms
 Congenital Abnormalities Antibodies  >3 publications with FBLN4 and Congenital Abnormalities
 Cardiovascular Abnormalities Antibodies  >1 publications with FBLN4 and Cardiovascular Abnormalities
 Cell Transformation, Neoplastic Antibodies  >1 publications with FBLN4 and Cell Transformation, Neoplastic
 Endometrial Neoplasms Antibodies  >1 publications with FBLN4 and Endometrial Neoplasms

Organs/Tissues associated with FBLN4 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >5 publications with FBLN4 and Skin
 Vascular Antibodies  >2 publications with FBLN4 and Vascular
 Eye Antibodies  >2 publications with FBLN4 and Eye
 Stomach Antibodies  >1 publications with FBLN4 and Stomach
 Lung Antibodies  >1 publications with FBLN4 and Lung
 Embryonic Tissue Antibodies  >1 publications with FBLN4 and Embryonic Tissue
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