Interleukin 1 Delta (FIL1d) ELISA Kit for Human

Name: Human FIL1d ELISA Kit; Interleukin 1 Delta; MyBioSource
Brand: MyBioSource
SKU: MBS459339
Price: 440 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS459339

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to FIL1d. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to FIL1d.… More details

$440 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Interleukin 1 Delta (FIL1d), ELISA Kit

Full Product Name

Human Interleukin 1 Delta (FIL1d) ELISA Kit

Product Gene Name

FIL1d elisa kit

Product Synonym Names

IL1HY1; IL36RN; IL36Ra; IL1RP3; IL1L1; IL1F5; Interleukin 1 Family, Member 5; Interleukin-1 HY1; IL-1 Related Protein 3; Interleukin 36 Receptor Antagonist

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates or Other Biological Fluids.

Detection Range

15.6-1000pg/mL

Sensitivity

5.7pg/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

16,962 Da

OMIM

605507

3D Structure

ModBase 3D Structure for Q9UBH0

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of FIL1d elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FIL1d purchase

MBS459339 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 1 Delta (FIL1d) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FIL1d. The ELISA analytical biochemical technique of the MBS459339 kit is based on FIL1d antibody-FIL1d antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FIL1d antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FIL1d. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FIL1d. It may not necessarily be applicable to this product.

NCBI GI #

6912432

NCBI GeneID

26525

NCBI Accession #

NP_036407.1

UniProt Primary Accession #

Q9UBH0

UniProt Secondary Accession #

Q56AT9; Q7RTZ6; A8K2I4

UniProt Related Accession #

Q9UBH0

GenBank Nucleotide #

NM_012275.2

NCBI Official Full Name

interleukin-36 receptor antagonist protein

NCBI Official Synonym Full Names

interleukin 36 receptor antagonist

NCBI Official Symbol

IL36RN

NCBI Official Synonym Symbols

FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; IL-36Ra; PSORS14; FIL1(DELTA)

UniProt Protein Name

Interleukin-36 receptor antagonist protein

UniProt Synonym Protein Names

FIL1 delta; IL-1-related protein 3; IL-1RP3; Interleukin-1 HY1; IL-1HY1; Interleukin-1 delta; IL-1 delta; Interleukin-1 family member 5; IL-1F5; Interleukin-1 receptor antagonist homolog 1; IL-1ra homolog 1; Interleukin-1-like protein 1; IL-1L1

UniProt Gene Name

IL36RN

UniProt Synonym Gene Names

FIL1D; IL1F5; IL1HY1; IL1L1; IL1RP3; IL-1RP3; IL-1HY1; IL-1 delta; IL-1F5; IL-1ra homolog 1; IL-1L1

NCBI Protein Information

interleukin-36 receptor antagonist protein

NCBI Summary for FIL1d

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

UniProt Comments for FIL1d

Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Research Articles on FIL1d

1. Using different blood leukocyte and skin resident cell preparations, and recombinant proteins, the authors have identified that neutrophil elastase, but not other neutrophil derived proteases, cleaves IL-36Ra into its highly active antagonistic form.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with FIL1d elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>9 publications with FIL1d and Inflammation
Hypersensitivity Antibodies	>4 publications with FIL1d and Hypersensitivity
Autoimmune Diseases Antibodies	>2 publications with FIL1d and Autoimmune Diseases
Congenital Abnormalities Antibodies	>2 publications with FIL1d and Congenital Abnormalities
Necrosis Antibodies	>2 publications with FIL1d and Necrosis
Disease Models, Animal Antibodies	>2 publications with FIL1d and Disease Models, Animal
Leukocytosis Antibodies	>1 publications with FIL1d and Leukocytosis
Heart Diseases Antibodies	>1 publications with FIL1d and Heart Diseases
Lung Diseases Antibodies	>1 publications with FIL1d and Lung Diseases

Organs/Tissues associated with FIL1d elisa kit

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>2 publications with FIL1d and Lung
Muscle Antibodies	>2 publications with FIL1d and Muscle
Testis Antibodies	>1 publications with FIL1d and Testis
Cervix Antibodies	>1 publications with FIL1d and Cervix
Mouth Antibodies	>1 publications with FIL1d and Mouth
Parathyroid Antibodies	>1 publications with FIL1d and Parathyroid
Placenta Antibodies	>1 publications with FIL1d and Placenta