Growth Arrest Specific Protein 6 (GAS6) ELISA Kit for Human

Name: Human GAS6 ELISA Kit; Growth Arrest Specific Protein 6; MyBioSource
Brand: MyBioSource
SKU: MBS459495
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS459495

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to GAS6. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to GAS6.… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Growth Arrest Specific Protein 6 (GAS6), ELISA Kit

Full Product Name

Human Growth Arrest Specific Protein 6 (GAS6) ELISA Kit

Product Gene Name

GAS6 elisa kit

Product Synonym Names

AXLLG; AXSF; AXL Stimulatory Factor; AXL receptor tyrosine kinase ligand

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates or Other Biological Fluids.

Detection Range

6.25-400pg/mL

Sensitivity

2.45pg/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

41,986 Da

OMIM

600441

3D Structure

ModBase 3D Structure for Q14393

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of GAS6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAS6 purchase

MBS459495 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Growth Arrest Specific Protein 6 (GAS6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GAS6. The ELISA analytical biochemical technique of the MBS459495 kit is based on GAS6 antibody-GAS6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GAS6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GAS6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GAS6. It may not necessarily be applicable to this product.

NCBI GI #

4557617

NCBI GeneID

2621

NCBI Accession #

NP_000811.1

UniProt Primary Accession #

Q14393

UniProt Secondary Accession #

Q6IMN1; Q7Z7N3; B3KRQ7; B3KVL4; E9PBL7

UniProt Related Accession #

Q14393

GenBank Nucleotide #

NM_000820.3

NCBI Official Full Name

growth arrest-specific protein 6

NCBI Official Synonym Full Names

growth arrest specific 6

NCBI Official Symbol

GAS6

NCBI Official Synonym Symbols

AXSF; AXLLG

UniProt Protein Name

Growth arrest-specific protein 6

UniProt Synonym Protein Names

AXL receptor tyrosine kinase ligand

Protein Family

Growth arrest-specific protein

UniProt Gene Name

GAS6

UniProt Synonym Gene Names

AXLLG; GAS-6

NCBI Protein Information

growth arrest-specific protein 6

NCBI Summary for GAS6

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014]

UniProt Comments for GAS6

Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Research Articles on GAS6

1. The anti-angiogenic effect of luteolin may be associated with the inhibition of the Gas6/Axl pathway and its downstream phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathways.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GAS6 elisa kit

Reference Product	PubMed Publications
AXL elisa kit	>212 publications with GAS6 and AXL
TYRO3 elisa kit	>83 publications with GAS6 and TYRO3
MERTK elisa kit	>55 publications with GAS6 and MERTK

Pathways associated with GAS6 elisa kit

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Gamma-carboxylation Of Protein Precursors Pathway antibodies	Gamma-carboxylation Of Protein Precursors Pathway Diagram
Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway antibodies	Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies	PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Platelet Degranulation Pathway antibodies	Platelet Degranulation Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram
Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway antibodies	Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway Diagram

Diseases associated with GAS6 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>58 publications with GAS6 and Neoplasms
Inflammation Antibodies	>49 publications with GAS6 and Inflammation
Cardiovascular Diseases Antibodies	>44 publications with GAS6 and Cardiovascular Diseases
Necrosis Antibodies	>28 publications with GAS6 and Necrosis
Thrombosis Antibodies	>28 publications with GAS6 and Thrombosis
Disease Models, Animal Antibodies	>25 publications with GAS6 and Disease Models, Animal
Kidney Diseases Antibodies	>22 publications with GAS6 and Kidney Diseases
Neoplasms, Experimental Antibodies	>12 publications with GAS6 and Neoplasms, Experimental
Prostatic Diseases Antibodies	>8 publications with GAS6 and Prostatic Diseases
Adenocarcinoma Antibodies	>8 publications with GAS6 and Adenocarcinoma

Organs/Tissues associated with GAS6 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>92 publications with GAS6 and Blood
Vascular Antibodies	>70 publications with GAS6 and Vascular
Muscle Antibodies	>44 publications with GAS6 and Muscle
Bone Antibodies	>39 publications with GAS6 and Bone
Kidney Antibodies	>31 publications with GAS6 and Kidney
Brain Antibodies	>26 publications with GAS6 and Brain
Bone Marrow Antibodies	>23 publications with GAS6 and Bone Marrow
Liver Antibodies	>20 publications with GAS6 and Liver
Eye Antibodies	>14 publications with GAS6 and Eye
Embryonic Tissue Antibodies	>14 publications with GAS6 and Embryonic Tissue