Glycophorin A (GYPA) ELISA Kit for Human

Name: Human GYPA ELISA Kit; Glycophorin A; MyBioSource
Brand: MyBioSource
SKU: MBS459769
Price: 525 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS459769

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to GYPA. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to GYPA.… More details

$525 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Glycophorin A (GYPA), ELISA Kit

Full Product Name

Human Glycophorin A (GYPA) ELISA Kit

Product Gene Name

GYPA elisa kit

Product Synonym Names

CD235a; MN; MNS; GPA; GPErik; GPSAT; PAS-2; GpMiIII; HGpMiIII; HGpMiV; HGpMiX; HGpMiXI; HGpSta; Sialoglycoprotein alpha; MN sialoglycoprotein

Species Reactivity

Human

Assay Type

Sandwich

Samples

Tissue Homogenates, Cell Lysates or Other Biological Fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.113ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

13,000 Da

OMIM

111300

3D Structure

ModBase 3D Structure for P02724

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of GYPA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GYPA purchase

MBS459769 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glycophorin A (GYPA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GYPA. The ELISA analytical biochemical technique of the MBS459769 kit is based on GYPA antibody-GYPA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GYPA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GYPA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GYPA. It may not necessarily be applicable to this product.

NCBI GI #

815891063

NCBI GeneID

2993

NCBI Accession #

NP_001295119.1

UniProt Primary Accession #

P02724

UniProt Secondary Accession #

Q9BS51; A8K3E6; B8Q182; B8Q185

UniProt Related Accession #

P02724

GenBank Nucleotide #

NM_001308190.1

NCBI Official Full Name

glycophorin-A isoform 3

NCBI Official Synonym Full Names

glycophorin A (MNS blood group)

NCBI Official Symbol

GYPA

NCBI Official Synonym Symbols

MN; GPA; MNS; GPSAT; PAS-2; CD235a; GPErik; HGpMiV; HGpMiXI; HGpSta(C)

UniProt Protein Name

Glycophorin-A

UniProt Synonym Protein Names

MN sialoglycoprotein; PAS-2; Sialoglycoprotein alpha; CD_antigen: CD235a

Protein Family

Glycophorin

UniProt Gene Name

GYPA

UniProt Synonym Gene Names

GPA

NCBI Protein Information

glycophorin-A

NCBI Summary for GYPA

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]

UniProt Comments for GYPA

Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).

Research Articles on GYPA

1. a complex structural rearrangement involving the loss of GYPB and gain of two GYPB-A hybrid genes reduces the risk of severe malaria by 40% and has recently increased in frequency in parts of Kenya

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GYPA elisa kit

Reference Product	PubMed Publications
CD34 elisa kit	>7 publications with GYPA and CD34
GYPC elisa kit	>3 publications with GYPA and GYPC
CD36 elisa kit	>2 publications with GYPA and CD36
SLC4A1 elisa kit	>2 publications with GYPA and SLC4A1
ITGA2B elisa kit	>1 publications with GYPA and ITGA2B

Pathways associated with GYPA elisa kit

Products by Pathway	Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Malaria Pathway antibodies	Malaria Pathway Diagram
Malaria Pathway antibodies	Malaria Pathway Diagram

Diseases associated with GYPA elisa kit

Disease Name	Pubmed Publications
Malaria Antibodies	>8 publications with GYPA and Malaria
Anemia Antibodies	>7 publications with GYPA and Anemia
Cardiovascular Diseases Antibodies	>4 publications with GYPA and Cardiovascular Diseases
Vascular Diseases Antibodies	>4 publications with GYPA and Vascular Diseases
Necrosis Antibodies	>4 publications with GYPA and Necrosis
Inflammation Antibodies	>4 publications with GYPA and Inflammation
Immune System Diseases Antibodies	>3 publications with GYPA and Immune System Diseases
Heart Diseases Antibodies	>2 publications with GYPA and Heart Diseases
Liver Diseases Antibodies	>2 publications with GYPA and Liver Diseases
Atherosclerosis Antibodies	>2 publications with GYPA and Atherosclerosis

Organs/Tissues associated with GYPA elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>83 publications with GYPA and Blood
Bone Marrow Antibodies	>7 publications with GYPA and Bone Marrow
Kidney Antibodies	>3 publications with GYPA and Kidney
Liver Antibodies	>3 publications with GYPA and Liver
Embryonic Tissue Antibodies	>2 publications with GYPA and Embryonic Tissue
Spleen Antibodies	>1 publications with GYPA and Spleen
Heart Antibodies	>1 publications with GYPA and Heart
Placenta Antibodies	>1 publications with GYPA and Placenta