Histone Acetyltransferase 1 (HAT1) ELISA Kit for Human

Name: Human HAT1 ELISA Kit; Histone Acetyltransferase 1; MyBioSource
Brand: MyBioSource
SKU: MBS459796
Price: 525 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS459796

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to HAT1. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to HAT1.… More details

$525 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Histone Acetyltransferase 1 (HAT1), ELISA Kit

Full Product Name

Human Histone Acetyltransferase 1 (HAT1) ELISA Kit

Product Gene Name

HAT1 elisa kit

Product Synonym Names

KAT1; Histone acetyltransferase type B catalytic subunit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Tissue Homogenates or Other Biological Fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.103ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

39,786 Da

OMIM

603053

3D Structure

ModBase 3D Structure for O14929

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of HAT1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAT1 purchase

MBS459796 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Histone Acetyltransferase 1 (HAT1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HAT1. The ELISA analytical biochemical technique of the MBS459796 kit is based on HAT1 antibody-HAT1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HAT1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HAT1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HAT1. It may not necessarily be applicable to this product.

NCBI GI #

4504341

NCBI GeneID

8520

NCBI Accession #

NP_003633.1

UniProt Primary Accession #

O14929

UniProt Secondary Accession #

Q49A44; Q53QF0; Q53SU4; Q6P594; Q8WWB9

UniProt Related Accession #

O14929

GenBank Nucleotide #

NM_003642.3

NCBI Official Full Name

histone acetyltransferase type B catalytic subunit

NCBI Official Synonym Full Names

histone acetyltransferase 1

NCBI Official Symbol

HAT1

NCBI Official Synonym Symbols

KAT1

UniProt Protein Name

Histone acetyltransferase type B catalytic subunit

UniProt Synonym Protein Names

Histone acetyltransferase 1

Protein Family

Histone acetyltransferase

UniProt Gene Name

HAT1

UniProt Synonym Gene Names

KAT1

NCBI Protein Information

histone acetyltransferase type B catalytic subunit

NCBI Summary for HAT1

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]

UniProt Comments for HAT1

Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.

Research Articles on HAT1

1. HAT1 was upregulated in hepatocellular carcinoma.HAT1 acts as an oncogenic protein promoting cell proliferation and inducing cisplatin resistance in hepatocellular carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HAT1 elisa kit

Products by Pathway	Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
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Diseases associated with HAT1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with HAT1 and Neoplasms
Proteinuria Antibodies	>2 publications with HAT1 and Proteinuria
Neoplasms, Experimental Antibodies	>1 publications with HAT1 and Neoplasms, Experimental
Prostatic Diseases Antibodies	>1 publications with HAT1 and Prostatic Diseases
Carcinoma Antibodies	>1 publications with HAT1 and Carcinoma
Lung Neoplasms Antibodies	>1 publications with HAT1 and Lung Neoplasms
Hypertrophy Antibodies	>1 publications with HAT1 and Hypertrophy
Kidney Diseases Antibodies	>1 publications with HAT1 and Kidney Diseases
Prostatic Neoplasms Antibodies	>1 publications with HAT1 and Prostatic Neoplasms
Adenocarcinoma Antibodies	>1 publications with HAT1 and Adenocarcinoma

Organs/Tissues associated with HAT1 elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>4 publications with HAT1 and Muscle
Heart Antibodies	>4 publications with HAT1 and Heart
Lung Antibodies	>3 publications with HAT1 and Lung
Brain Antibodies	>3 publications with HAT1 and Brain
Kidney Antibodies	>3 publications with HAT1 and Kidney
Vascular Antibodies	>2 publications with HAT1 and Vascular
Blood Antibodies	>2 publications with HAT1 and Blood
Liver Antibodies	>2 publications with HAT1 and Liver
Ovary Antibodies	>1 publications with HAT1 and Ovary
Intestine Antibodies	>1 publications with HAT1 and Intestine