Rabbit Anti-KIF6 Polyclonal Antibody – Cat# MBS460547

KIF6 Antibody – Rabbit Polyclonal

Name: KIF6 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS460547
Price: 355 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS460547

KIF6 belongs to the kinesin-like protein family. There are four named isoforms. The KIF6 719Arg polymorphism in the KIF6 gene might be associated with an increased risk of coronary artery disease, thus, the KIF6, together with Apolipoprotein E, lipoprotein… More details

$355 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KIF6, Polyclonal Antibody

Full Product Name

Rabbit anti KIF6 Polyclonal Antibody

Product Gene Name

anti-KIF6 antibody

Product Synonym Names

Kinesin family member 6

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.

Purity/Purification

Purified by Epitope Affinity Purification

Specificity

This antibody recognizes ~94 kDa of human/mouse KIF6 protein. The other species are not tested.

Preparation and Storage

The antibodies are stable for 12 months from date of receipt when stored at -20 degree C. The antibodies can be stored at 2 degree C - 8 degree C for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Molecular Weight

19,809 Da

OMIM

AK123217 mRNA

3D Structure

ModBase 3D Structure for Q6ZMV9

Preparation

A synthetic peptide corresponding to internal sequence of human KIF6.

Applications Tested/Suitable for anti-KIF6 antibody

ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

Application Notes for anti-KIF6 antibody

ELISA: 0.01-0.1 ug/ml
Flow Cytometry: 5-10 ug/ml
Immunohistochemistry: 2-10 ug/ml
Immunoprecipitation: 2-5 ug/ml
Western Blot: 0.1-1 ug/ml

Product References and Citations for anti-KIF6 antibody

Iakoubova, O.A., et al. Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials. J. Am. Coll. Cardiol. 51 (4), 435-443 (2008)

Other Notes

Small volumes of anti-KIF6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIF6 purchase

MBS460547 is an antibody targeting KIF6. Also known as Rabbit anti KIF6 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KIF6. It may not necessarily be applicable to this product.

NCBI GI #

157502184

NCBI GeneID

221458

NCBI Accession #

NP_659464.3

UniProt Primary Accession #

Q6ZMV9

UniProt Secondary Accession #

Q2MDE3; Q2MDE4; Q5T8J6; Q6ZWE3; Q86T87; Q8WTV4

UniProt Related Accession #

Q6ZMV9

GenBank Nucleotide #

NM_145027.5

NCBI Official Full Name

kinesin-like protein KIF6 isoform 1

NCBI Official Synonym Full Names

kinesin family member 6

NCBI Official Symbol

KIF6

NCBI Official Synonym Symbols

C6orf102; dJ137F1.4; dJ188D3.1; dJ1043E3.1

UniProt Protein Name

Kinesin-like protein KIF6

Protein Family

Kinesin-like protein

UniProt Gene Name

KIF6

UniProt Synonym Gene Names

C6orf102

NCBI Protein Information

kinesin-like protein KIF6

NCBI Summary for KIF6

This gene encodes a member of a family of molecular motors which are involved in intracellular transport of protein complexes, membrane organelles, and messenger ribonucleic acid along microtubules. Kinesins function as homodimeric molecules with two N-terminal head domains that move along microtubules and two C-terminal tail domains that interact with the transported cargo, either directly or indirectly, through adapter molecules. This gene is ubiquitously expressed in coronary arteries and other vascular tissue. A naturally occurring mutation in this gene is associated with coronary heart disease. [provided by RefSeq, May 2017]

UniProt Comments for KIF6

KIF6: Belongs to the kinesin-like protein family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 6p21.2

Cellular Component: kinesin complex

Molecular Function: ATPase activity; microtubule motor activity; protein binding

Biological Process: microtubule-based movement

Research Articles on KIF6

1. The absence of Trp719Arg polymorphism association with coronary artery disease (CAD) and CAD in stratified myocardial infarction cases indicates that the polymorphism is not associated with an increased risk among CAD patients from the Eastern Province of Saudi Arabia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KIF6 antibody

Reference Product	PubMed Publications
MYH15 antibody	>2 publications with KIF6 and MYH15

Pathways associated with anti-KIF6 antibody

Products by Pathway	Pathway Diagram
COPI-dependent Golgi-to-ER Retrograde Traffic Pathway antibodies	COPI-dependent Golgi-to-ER Retrograde Traffic Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Golgi-to-ER Retrograde Transport Pathway antibodies	Golgi-to-ER Retrograde Transport Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway antibodies	Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway Diagram
Kinesins Pathway antibodies	Kinesins Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Vesicle-mediated Transport Pathway antibodies	Vesicle-mediated Transport Pathway Diagram

Diseases associated with anti-KIF6 antibody

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>36 publications with KIF6 and Cardiovascular Diseases
Vascular Diseases Antibodies	>33 publications with KIF6 and Vascular Diseases
Myocardial Infarction Antibodies	>23 publications with KIF6 and Myocardial Infarction
Atherosclerosis Antibodies	>10 publications with KIF6 and Atherosclerosis
Hypertension Antibodies	>2 publications with KIF6 and Hypertension
Neurobehavioral Manifestations Antibodies	>1 publications with KIF6 and Neurobehavioral Manifestations
Neurodegenerative Diseases Antibodies	>1 publications with KIF6 and Neurodegenerative Diseases
Kidney Diseases Antibodies	>1 publications with KIF6 and Kidney Diseases
Cognition Disorders Antibodies	>1 publications with KIF6 and Cognition Disorders
Disease Models, Animal Antibodies	>1 publications with KIF6 and Disease Models, Animal

Organs/Tissues associated with anti-KIF6 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with KIF6 and Lung