MCV Antibody – Mouse Monoclonal

MCV (mutated citrullinated vimentin) and cyclic citrullinated peptides (CCPs) are potential reliable biomarkers for rheumatoid arthritis (RA). The usefulness of rheumatoid factor (RF) is hampered by low specificity and possible absence in the first year of the disease. Antibodies to cyclic citrullinated peptide (CCP) have high specificity, but low sensitivity for early RA, and CCP is not expressed in the synovial membranes. MCV might be a useful addition to the array of diagnostic tools for RA. Anti-MCV antibodies recognize a protein that originates from apoptotic macrophages and is present in the synovium of patients with RA.

Small volumes of anti-MCV antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS460969 is an antibody targeting MCV. Also known as Mouse anti MCV Monoclonal Antibody. Reactive in Human. Host: Mouse.