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ER (pS167) Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS462045

ER (estrogen receptor) belongs to a member of the steroid receptor superfamily. It contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2,… More details

$345 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ER (pS167), Antibody
Full Product Name
Rabbit anti ER (pSer 167), Phosphospecific
Product Gene Name
Product Synonym Names
Rabbit anti-ER (pSer167) (Phosphospecific); Estrogen Receptor
Host
Rabbit
Species Reactivity
Human
Form/Format
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
Purity/Purification
The Rabbit IgG is purified by Site-specific Epitope Affinity Purification.
Concentration
Size: 100 ug/200 ul (lot specific)
Specificity
This antibody recognizes ~67 kDa of human estrogen receptor at the phosphorylation site of Ser 167. It does not cross react to non-hosphorylated peptide. This antibody reacts with human. The other species are not tested.
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Molecular Weight
67 kDa
Antigen Preparation
A synthetic peptide surrounding the epitope -LASTN- with a phosphorylation site of Ser167 of human estrogen receptor.
Positive Control
MCF-7
Cellular Location
Nuclear
Applications Tested/Suitable for anti-ER (pS167) antibody
ELISA, Western Blot
Application Notes for anti-ER (pS167) antibody
Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 1:200

Testing Data of anti-ER (pS167) antibody

Rabbit Anti-ER (pS167) Antibody – Cat# MBS462045

Product References and Citations for anti-ER (pS167) antibody

Dutertre M, Smith CL. 2003. Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains. Mol Endocrinol 17:1296-314.

Other Notes

Small volumes of anti-ER (pS167) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ER (pS167) purchase

MBS462045 is an antibody targeting ER (pS167). Also known as Rabbit anti ER (pSer 167), Phosphospecific. Reactive in Human. Host: Rabbit.
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