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LSP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS462157

Leukocyte-specific protein 1 (LSP1), an F-actin binding protein and a major downstream substrate of p38 mitogen-activated protein kinase as well as protein kinase C, is important in leukocyte chemotaxis. Two serine residues at positions 204 and 252 are… More details

$315 / 0.1 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LSP, Polyclonal Antibody
Full Product Name
Rabbit anti LSP1Polyclonal antibody
Product Gene Name
Product Synonym Names
Rabbit anti-- LSP1; Lymphocyte antigen; lymphocyte-specific protein 1 (LSP1);
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Purity/Purification
The Rabbit IgG is purified by Site-specific Epitope Affinity Purification.
Concentration
Size: 100 ug/200 ul (lot specific)
Specificity
This antibody recognizes ~52 kDa of human LSP1 protein. This antibody also reacts with mouse. The other species are not tested.
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Molecular Weight
~52 kDa
3D Structure
ModBase 3D Structure for P00804
Antigen Preparation
A synthetic peptide corresponding to the C-terminus of human lymphocyte-specific protein 1. This sequence is identical to mouse species
Positive Control
Mouse spleen tissue
Cellular Location
Cytoplasmic and membrane
Applications Tested/Suitable for anti-LSP antibody
ELISA, Western Blot, Immunohistochemistry
Application Notes for anti-LSP antibody
Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 2-5 ug/ml

Testing Data of anti-LSP antibody

Rabbit Anti-LSP Polyclonal Antibody – Cat# MBS462157

Product References and Citations for anti-LSP antibody

Lixin Liu, et al. LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration. (2005), JEM, 201 (3): 409-418.

Other Notes

Small volumes of anti-LSP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LSP purchase

MBS462157 is an antibody targeting LSP. Also known as Rabbit anti LSP1Polyclonal antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LSP. It may not necessarily be applicable to this product.

NCBI GI #
UniProt Primary Accession #
NCBI Official Full Name
lsp
UniProt Protein Name
Lipoprotein signal peptidase
UniProt Synonym Protein Names
Prolipoprotein signal peptidase; Signal peptidase II
Protein Family
UniProt Gene Name
lspA
UniProt Entry Name
LSPA_ECOLI

UniProt Comments for LSP

Function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins. HAMAP MF_00161

Catalytic activity: Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains. HAMAP MF_00161

Subcellular location: Cell inner membrane; Multi-pass membrane protein HAMAP MF_00161.

Sequence similarities: Belongs to the peptidase A8 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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