TUBULIN beta Antibody – Rabbit

Tubulin is the major building block of microtubules which is essential in cell structures, transportation and mitosis. This superfamily is composed of six distinct families. Alpha, beta, and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The abundance of Gamma tubulin is less than 1% of the level of either alpha or beta tubulin. It shares approximately 28-32% identity with alpha tubulin from various organisms and 32-36% identity with beta tubulins. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis and the microtubule cytoskeleton.

Wang, HW, Nogales E. Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly. Nature 435 (7044): 911-915, 2005.

Small volumes of anti-Tubulin beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS462189 is an antibody targeting Tubulin beta. Also known as Tubulin beta Epitope Specific Rabbit antibody. Reactive in Human, Mouse, Rat, Bovine, Canine. Host: Rabbit.