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CLAUDIN 10 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS462245

The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both… More details

$355 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Claudin 10, Antibody
Full Product Name
Rabbit anti Claudin 10 antibody
Product Gene Name
Product Synonym Names
Rabbit anti-Claudin 10
Host
Rabbit
Species Reactivity
Human, Rat, Mouse
Form/Format
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Purity/Purification
The rabbit antibody is purified by affinity purification.
Concentration
Size: 100 ug/200 ul (lot specific)
Specificity
This antibody reacts with human,rat and mouse. Others not tested.
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Molecular Weight
21 kDa
Chromosome Location
Chromosome: 13; NC_000013.10 (96085853..96232010). Location: 13q31-q34
3D Structure
ModBase 3D Structure for P78369
Antigen Preparation
A synthetic peptide from C-terminus of human claudin 10 protein.
Positive Control
Brain and Skeletal muscle
Cellular Location
Cellular junction/gap
Applications Tested/Suitable for anti-Claudin 10 antibody
Immunohistology
Application Notes for anti-Claudin 10 antibody
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 1-2 ug/ml

Testing Data of anti-Claudin 10 antibody

Rabbit Anti-CLAUDIN 10 Antibody – Cat# MBS462245

Product References and Citations for anti-Claudin 10 antibody

Hashizume A; Ueno T; Furuse M; Tsukita S; Nakanishi Y; Hieda Y (2004), Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn 231 (2), 425-431.

Other Notes

Small volumes of anti-Claudin 10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Claudin 10 purchase

MBS462245 is an antibody targeting Claudin 10. Also known as Rabbit anti Claudin 10 antibody. Reactive in Human, Rat, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Claudin 10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
claudin-10 isoform a_i1
NCBI Official Synonym Full Names
claudin 10
NCBI Official Symbol
CLDN10
NCBI Official Synonym Symbols
OSP-L; CPETRL3
UniProt Protein Name
Claudin-10
UniProt Synonym Protein Names
OSP-like protein
Protein Family
UniProt Gene Name
CLDN10
UniProt Entry Name
CLD10_HUMAN
NCBI Protein Information
claudin-10; OSP-like protein; OTTHUMP00000018561; OTTHUMP00000018562

NCBI Summary for Claudin 10

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.
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UniProt Comments for Claudin 10

Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity

Subcellular location: Cell junction › tight junction. Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the claudin family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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