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CD41/CD61 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS465049

CRC64 (FRaMon) recognizes complex-specific epitope but not dissociated GP IIb or GP IIIa. CRC64 inhibits platelet aggregation by blocking fibrinogen binding to GP IIb-IIIa. CRC64 does not react with platelets from patients with the hereditary deficiency of GP… More details

$395 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD41/CD61, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to CD41/CD61 (human)- Platelet glycoprotein complex IIb-IIIa, aIIbb3 integrin
Product Gene Name
anti-CD41/CD61 antibody
Product Synonym Names
anti-CD41/CD61 MAb (CRC64-FRaMon)
Clonality
Monoclonal
Isotype
Mouse IgG1 (k)
Clone Number
CRC64 (FRaMon)
Host
Mouse
Form/Format
0.1 mg in PBS/azide buffer
Purity/Purification
>95% (by PAGE). Purified from ascites by DEAE chromatography.
Concentration
3.3 mg/ml (lot specific)
Specificity
Human platelet membrane glycoprotein (GP) llb-llla (allb/b3 integrin, CD41/CD61), does not interact with human av/b3 integrin, or with dog rabbit GP llb-llla. Complex specific, inhibits glycoprotein llb-llla interaction with fibrinogen and other ligands, inhibits platelet aggregation.
Preparation and Storage
Store at +4 degree C for 3 months. For long-term storage, aliquot and store at -70 degree C. Avoid freeze/thaw cycles.
Ships on dry ice.
Immunogen
Human platelets
Applications Tested/Suitable for anti-CD41/CD61 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoblot (IB)

Product References and Citations for anti-CD41/CD61 antibody

Khaspekova et al, Br. J. Haematol. 1993, 85, 332-40; Mazurov et al., FEBS Lett., 1996, 391, 84-8; Byzova & Plow, J. Biol. Chem. 1997, 272, 27183-8; Mazurov et al, Ter Arkhiv, 2001, No 9, 66-73 (in Russian); Mazurov et al, Platelets 2002 13, 465-77; Naimushin & Mazurov, Biochemistry (Moscow), 2003, 68, 250-259

Other Notes

Small volumes of anti-CD41/CD61 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD41/CD61 purchase

MBS465049 is an antibody targeting CD41/CD61. Also known as Monoclonal Antibody to CD41/CD61 (human)- Platelet glycoprotein complex IIb-IIIa, aIIbb3 integrin. Host: Mouse.
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