Glycoprotein V, Platelet (GP5) ELISA Kit for Human

Name: Human GP5 ELISA Kit; Glycoprotein V, Platelet; MyBioSource
Brand: MyBioSource
SKU: MBS046813
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS046813

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of GP5 (hereafter termed "analyte") in… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Glycoprotein V, Platelet (GP5), ELISA Kit

Full Product Name

Human Glycoprotein V, Platelet ELISA Kit

Product Gene Name

GP5 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Detection Range

0.625ng/ml-20ng/ml

Sensitivity

0.1ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

60,959 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (194115550..194119995, complement). Location: 3q29

OMIM

173511

3D Structure

ModBase 3D Structure for P40197

Other Notes

Small volumes of GP5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GP5 purchase

MBS046813 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glycoprotein V, Platelet (GP5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GP5. The ELISA analytical biochemical technique of the MBS046813 kit is based on GP5 antibody-GP5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GP5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GP5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GP5. It may not necessarily be applicable to this product.

NCBI GI #

269819656

NCBI GeneID

2814

NCBI Accession #

ACZ44929.1

UniProt Primary Accession #

P40197

UniProt Related Accession #

P40197

NCBI Official Full Name

glycoprotein V (platelet)

NCBI Official Synonym Full Names

glycoprotein V (platelet)

NCBI Official Symbol

GP5

NCBI Official Synonym Symbols

GPV; CD42d

UniProt Protein Name

Platelet glycoprotein V

UniProt Synonym Protein Names

Glycoprotein 5

Protein Family

Glycoprotein

UniProt Gene Name

GP5

UniProt Synonym Gene Names

GPV

UniProt Entry Name

GPV_HUMAN

NCBI Protein Information

platelet glycoprotein V; glycoprotein 5

NCBI Summary for GP5

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]

UniProt Comments for GP5

GPV: The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: collagen binding

Biological Process: platelet activation; cell-matrix adhesion; cell adhesion; blood coagulation; blood coagulation, intrinsic pathway

Research Articles on GP5

1. GPIIb/IIIa is the primary receptor set involved in platelet adhesion to adsorbed fibrinogen and serum albumin irrespective of their degree of adsorption-induced unfolding, while the GPIb-IX-V receptor complex plays an insignificant role.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GP5 elisa kit

Reference Product	PubMed Publications
GP9 elisa kit	>2 publications with GP5 and GP9

Pathways associated with GP5 elisa kit

Products by Pathway	Pathway Diagram
ECM-receptor Interaction Pathway antibodies	ECM-receptor Interaction Pathway Diagram
ECM-receptor Interaction Pathway antibodies	ECM-receptor Interaction Pathway Diagram
Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies	Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
GP1b-IX-V Activation Signalling Pathway antibodies	GP1b-IX-V Activation Signalling Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Intrinsic Pathway antibodies	Intrinsic Pathway Diagram
Platelet Adhesion To Exposed Collagen Pathway antibodies	Platelet Adhesion To Exposed Collagen Pathway Diagram
Platelet Aggregation (Plug Formation) Pathway antibodies	Platelet Aggregation (Plug Formation) Pathway Diagram

Diseases associated with GP5 elisa kit

Disease Name	Pubmed Publications
Carcinoma Antibodies	>214 publications with GP5 and Carcinoma
Uterine Cervical Neoplasms Antibodies	>166 publications with GP5 and Uterine Cervical Neoplasms
Precancerous Conditions Antibodies	>28 publications with GP5 and Precancerous Conditions
Skin Diseases Antibodies	>19 publications with GP5 and Skin Diseases
Inflammation Antibodies	>16 publications with GP5 and Inflammation
Hyperplasia Antibodies	>9 publications with GP5 and Hyperplasia
Breast Neoplasms Antibodies	>6 publications with GP5 and Breast Neoplasms
Cell Transformation, Neoplastic Antibodies	>4 publications with GP5 and Cell Transformation, Neoplastic
Urologic Neoplasms Antibodies	>3 publications with GP5 and Urologic Neoplasms
Lung Diseases Antibodies	>3 publications with GP5 and Lung Diseases

Organs/Tissues associated with GP5 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Marrow Antibodies	>3 publications with GP5 and Bone Marrow