Protein Z Dependent Protease Inhibitor (ZPI) ELISA Kit for Cavy

Name: Cavy ZPI ELISA Kit; Protein Z Dependent Protease Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS046826
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS046826

MBS046826 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protein Z Dependent Protease Inhibitor (ZPI) ELISA Kit target analytes in biological samples. The concentration… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Protein Z Dependent Protease Inhibitor (ZPI), ELISA Kit

Full Product Name

Cavy Protein Z Dependent Protease Inhibitor ELISA Kit

Product Gene Name

ZPI elisa kit

Species Reactivity

Cavy

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

50,707 Da

Chromosome Location

Chromosome: 14; NC_000014.8 (94749650..94759596, complement). Location: 14q32.13

OMIM

602455

3D Structure

ModBase 3D Structure for Q9UK55

Other Notes

Small volumes of ZPI elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZPI. It may not necessarily be applicable to this product.

NCBI GI #

154759291

NCBI GeneID

51156

NCBI Accession #

NP_001094077.1

UniProt Primary Accession #

Q9UK55

UniProt Secondary Accession #

Q6UWX9; Q86U20; A5Z2A5

UniProt Related Accession #

Q9UK55

GenBank Nucleotide #

NM_001100607.2

NCBI Official Full Name

protein Z-dependent protease inhibitor

NCBI Official Synonym Full Names

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10

NCBI Official Symbol

SERPINA10

NCBI Official Synonym Symbols

PZI; ZPI

UniProt Protein Name

Protein Z-dependent protease inhibitor

UniProt Synonym Protein Names

Serpin A10

Protein Family

Protein Z-dependent protease inhibitor

UniProt Gene Name

SERPINA10

UniProt Synonym Gene Names

ZPI; PZ-dependent protease inhibitor; PZI

UniProt Entry Name

ZPI_HUMAN

NCBI Protein Information

protein Z-dependent protease inhibitor; serpin A10; PZ-dependent protease inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10

NCBI Summary for ZPI

The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010]

UniProt Comments for ZPI

SERPINA10: Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Belongs to the serpin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 14q32.13

Cellular Component: extracellular space

Molecular Function: heparin binding; serine-type endopeptidase inhibitor activity

Biological Process: regulation of acrosome reaction; blood coagulation

Research Articles on ZPI

1. structural features within residues of the 39-loop contribute to the resistance of FIXa to inhibition by plasma inhibitors ZPI and TFPI.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ZPI elisa kit

Reference Product	PubMed Publications
PROZ elisa kit	>1 publications with ZPI and PROZ

Diseases associated with ZPI elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>18 publications with ZPI and Cardiovascular Diseases
Venous Thrombosis Antibodies	>11 publications with ZPI and Venous Thrombosis
Brain Diseases Antibodies	>3 publications with ZPI and Brain Diseases
Liver Neoplasms Antibodies	>2 publications with ZPI and Liver Neoplasms
Liver Diseases Antibodies	>2 publications with ZPI and Liver Diseases
Thrombophilia Antibodies	>2 publications with ZPI and Thrombophilia
Mental Disorders Antibodies	>1 publications with ZPI and Mental Disorders
Hemorrhage Antibodies	>1 publications with ZPI and Hemorrhage

Organs/Tissues associated with ZPI elisa kit

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>4 publications with ZPI and Heart
Liver Antibodies	>4 publications with ZPI and Liver