Mouse Anti-CaMKIV Monoclonal Antibody – Cat# MBS475040

Western blot detection of CaMKIV in Romas and Jurkat cell lysates using CaMKIV mouse mAb (1:1000 diluted).Predicted band size:52KDa.Observed band size:55KDa.

CaMKIV Antibody – Mouse Monoclonal

Name: CaMKIV Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS475040
Price: 525 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS475040

Entrez Summary: The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca (2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue… More details

$525 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CaMKIV, Monoclonal Antibody

Full Product Name

Anti-CaMKIV Mouse mAb

Product Gene Name

anti-CaMKIV antibody

Product Synonym Gene Name

camk4; IV; caMK; CaMK IV; CaMK-GR

Product Synonym Names

Brain Ca (2) calmodulin dependent protein kinase type 4; Brain Ca (2) calmodulin dependent protein kinase type IV; Brain Ca -calmodulin dependent protein kinase type IV; Calcium / calmodulin dependent protein kinase type 4 catalytic chain; Calcium / calmodulin dependent protein kinase type IV catalytic chain; Calcium/calmodulin dependent protein kinase IV; Calcium/calmodulin dependent protein kinase type IV; Calcium/calmodulin-dependent protein kinase type IV; CAM kinase 4; CAM kinase GR; CAM kinase IV; CAM kinase-GR; CaMK 4; CAMK GR; CaMK IV; CaMK4; CaMKGR; IV; KCC4_HUMAN; MGC36771

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

3C10-D5-G7

Host

Mouse
Source: Human

Species Reactivity

Human

Sensitivity

This antibody detects endogenous levels of CaMKIV and does not cross-react with related proteins.

Form/Format

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol

Purity/Purification

Affinity Purified

Concentration

1mg/ml (lot specific)

Molecular Weight

OMIM

D30742 mRNA

3D Structure

ModBase 3D Structure for Q16566

Immunogen

Purified recombinant human CaMKIV protein fragments expressed in E Coli.

Sequence Similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. Contains 1 protein kinase domain.

Subunit Structure

Monomer By similarity. Interacts with protein phosphatase 2A (PPP2CA/PPP2CB); the interaction is mutually exclusive with binding to Ca2+/calmodulin.

Subcellular Location

Cytoplasm. Nucleus

Applications Tested/Suitable for anti-CaMKIV antibody

Western Blot (WB)

Application Notes for anti-CaMKIV antibody

WB: 1:1000

Other Notes

Small volumes of anti-CaMKIV antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CaMKIV purchase

MBS475040 is an antibody targeting CaMKIV. Also known as Anti-CaMKIV Mouse mAb. Reactive in Human. Host: Mouse
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CaMKIV. It may not necessarily be applicable to this product.

NCBI GI #

1020738596

NCBI GeneID

814

NCBI Accession #

NP_001310303.1

UniProt Primary Accession #

Q16566

UniProt Secondary Accession #

D3DSZ7

UniProt Related Accession #

Q16566

GenBank Nucleotide #

NM_001744.3

NCBI Official Full Name

calcium/calmodulin-dependent protein kinase type IV isoform 1

NCBI Official Synonym Full Names

calcium/calmodulin dependent protein kinase IV

NCBI Official Symbol

CAMK4

NCBI Official Synonym Symbols

caMK; CaMK IV; CaMK-GR

UniProt Protein Name

Calcium/calmodulin-dependent protein kinase type IV

UniProt Synonym Protein Names

CaM kinase-GR

UniProt Gene Name

CAMK4

UniProt Synonym Gene Names

CAMK; CAMK-GR; CAMKIV; CaMK IV

NCBI Protein Information

calcium/calmodulin-dependent protein kinase type IV

NCBI Summary for CaMKIV

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008]

UniProt Comments for CaMKIV

CAMK4: a protein kinase of the CAMK1 family. Implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Two alternatively sliced isoforms have been described.

Protein type: CAMK group; CAMK1 family; EC 2.7.11.17; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 5q22.1

Cellular Component: cytoplasm; cytosol; nucleolus; nucleoplasm; nucleus

Molecular Function: calcium-dependent protein serine/threonine kinase activity; calmodulin binding; calmodulin-dependent protein kinase activity

Biological Process: long-term memory; myeloid dendritic cell cytokine production; myeloid dendritic cell differentiation; peptidyl-serine phosphorylation; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of osteoclast differentiation; regulation of T cell differentiation in the thymus; signal transduction

Research Articles on CaMKIV

1. The T-allele of rs10491334 in CAMK4 was associated with hypertension in the Uygur group.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CaMKIV antibody

Reference Product	PubMed Publications
CREB1 antibody	>8 publications with CaMKIV and CREB1
CREBBP antibody	>6 publications with CaMKIV and CREBBP
CAMKK2 antibody	>6 publications with CaMKIV and CAMKK2
MEF2A antibody	>2 publications with CaMKIV and MEF2A
CAMKK1 antibody	>2 publications with CaMKIV and CAMKK1
ATF2 antibody	>2 publications with CaMKIV and ATF2
CABIN1 antibody	>1 publications with CaMKIV and CABIN1
HDAC4 antibody	>1 publications with CaMKIV and HDAC4
STMN1 antibody	>1 publications with CaMKIV and STMN1
MEF2D antibody	>1 publications with CaMKIV and MEF2D

Pathways associated with anti-CaMKIV antibody

Products by Pathway	Pathway Diagram
Activation Of CaMK IV Pathway antibodies	Activation Of CaMK IV Pathway Diagram
Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies	Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Aldosterone Synthesis And Secretion Pathway antibodies	Aldosterone Synthesis And Secretion Pathway Diagram
Aldosterone Synthesis And Secretion Pathway antibodies	Aldosterone Synthesis And Secretion Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway antibodies	Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway Diagram
CREB Phosphorylation Through The Activation Of CaMKK Pathway antibodies	CREB Phosphorylation Through The Activation Of CaMKK Pathway Diagram

Diseases associated with anti-CaMKIV antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>28 publications with CaMKIV and Nervous System Diseases
Brain Diseases Antibodies	>16 publications with CaMKIV and Brain Diseases
Cardiovascular Diseases Antibodies	>14 publications with CaMKIV and Cardiovascular Diseases
Inflammation Antibodies	>12 publications with CaMKIV and Inflammation
Mental Disorders Antibodies	>12 publications with CaMKIV and Mental Disorders
Pain Antibodies	>11 publications with CaMKIV and Pain
Memory Disorders Antibodies	>8 publications with CaMKIV and Memory Disorders
Hypertrophy Antibodies	>7 publications with CaMKIV and Hypertrophy
Necrosis Antibodies	>7 publications with CaMKIV and Necrosis
Learning Disorders Antibodies	>6 publications with CaMKIV and Learning Disorders

Organs/Tissues associated with anti-CaMKIV antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>144 publications with CaMKIV and Brain
Nerve Antibodies	>25 publications with CaMKIV and Nerve
Testis Antibodies	>13 publications with CaMKIV and Testis
Embryonic Tissue Antibodies	>9 publications with CaMKIV and Embryonic Tissue
Eye Antibodies	>5 publications with CaMKIV and Eye
Lung Antibodies	>3 publications with CaMKIV and Lung
Lymph Node Antibodies	>1 publications with CaMKIV and Lymph Node
Connective Tissue Antibodies	>1 publications with CaMKIV and Connective Tissue