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CDX2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS475083

Entrez Summary: This gene is a member of the caudal-related homeobox transcription factor gene family.The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation.This protein also plays a role in early… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CDX2, Monoclonal Antibody
Full Product Name
Anti-CDX2 Mouse mAb
Product Gene Name
Product Synonym Gene Name
CDX3; CDX-3.
Product Synonym Names
Caudal type homeo box 2; Caudal type homeo box transcription factor 2; Caudal type homeobox 2; Caudal type homeobox protein 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX 2; CDX 3; CDX-3; Cdx2; CDX2_HUMAN; CDX3; Homeobox protein CDX 2; Homeobox protein CDX-2; Homeobox protein CDX2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4F12-B3-H4
Host
Mouse
Source: Human
Species Reactivity
Human, Monkey
Sensitivity
This antibody detects endogenous levels of CDX2 and does not cross-react with related proteins.
Form/Format
Purified mouse monoclonal in PBS (pH 7.4) containing with 0.02% sodium azide & 50% glycerol.
Purity/Purification
Affinity Purified
Concentration
1.2mg/ml (lot specific)
Molecular Weight
34
OMIM
Y13709 mRNA
3D Structure
ModBase 3D Structure for Q99626
Immunogen
Purified recombinant human CDX2 protein fragments expressed in E Coli.
Sequence Similarities
Belongs to the Caudal homeobox family.Contains 1 homeobox DNA-binding domain.
Subcellular Location
Nucleus
Applications Tested/Suitable for anti-CDX2 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
Application Notes for anti-CDX2 antibody
WB: 1:1000
ICC: 1:100

Western Blot (WB) of anti-CDX2 antibody

Western blot detection of CDX2 in Hela, COS7 and K562 cell lysates using CDX2 mouse mAb (1:1000 diluted).Predicted band size:34KDa.Observed band size:34KDa.
Mouse Anti-CDX2 Monoclonal Antibody – Cat# MBS475083

Immunocytochemistry (ICC) of anti-CDX2 antibody

Immunocytochemistry stain of Hela using CDX2 mouse mAb (1:100).
Mouse Anti-CDX2 Monoclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS475083

Immunoprecipitation (IP) of anti-CDX2 antibody

Immunoprecipitation analysis of Hela cell lysate using CDX2 mouse mAb.
Mouse Anti-CDX2 Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS475083

Other Notes

Small volumes of anti-CDX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDX2 purchase

MBS475083 is an antibody targeting CDX2. Also known as Anti-CDX2 Mouse mAb. Reactive in Human, Monkey. Host: Mouse
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CDX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein CDX-2
NCBI Official Synonym Full Names
caudal type homeobox 2
NCBI Official Symbol
CDX2
NCBI Official Synonym Symbols
CDX3; CDX-3; CDX2/AS
UniProt Protein Name
Homeobox protein CDX-2
UniProt Synonym Protein Names
CDX-3; Caudal-type homeobox protein 2
Protein Family
UniProt Gene Name
CDX2
UniProt Synonym Gene Names
CDX3
NCBI Protein Information
homeobox protein CDX-2

NCBI Summary for CDX2

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]
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UniProt Comments for CDX2

CDX2: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Belongs to the Caudal homeobox family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q12.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: transcription factor activity

Biological Process: anterior/posterior axis specification; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; regulation of somitogenesis; transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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