Rabbit Anti-PLSCR3 Monoclonal Antibody – Cat# MBS4752966

Western blot detection of PLSCR3 in K562,Hela cell lysates using PLSCR3 Rabbit mAb(1:1000 diluted). Predicted band size:32kDa. Observed band size:32kDa.

PLSCR3 Antibody – Rabbit Monoclonal

Name: PLSCR3 Antibody; Monoclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS4752966
Price: 525 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4752966

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot… More details

$525 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PLSCR3, Monoclonal Antibody

Full Product Name

PLSCR3 Rabbit mAb

Product Gene Name

anti-PLSCR3 antibody

Product Synonym Names

Phospholipid scramblase 3

Clonality

Monoclonal

Isotype

Rabbit IgG

Clone Number

R02-1B9

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Supplied in 50nM Tris-Glycine (pH7.4), 0.15M Nacl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Purity/Purification

Affinity purified

Specificity

Expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver. Gene expression databases

Preparation and Storage

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycle.

Molecular Weight

31,648 Da

OMIM

607611

3D Structure

ModBase 3D Structure for Q9NRY6

Immunogen

A synthetic peptide of human PLSCR3

Conjugation

Unconjugated

Modification

Unmodification

Subcellular Location

Membrane, Mitochondrion

Applications Tested/Suitable for anti-PLSCR3 antibody

Western Blot (WB)

Application Notes for anti-PLSCR3 antibody

WB: 1:1000-1:5000

Other Notes

Small volumes of anti-PLSCR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLSCR3 purchase

MBS4752966 is an antibody targeting PLSCR3. Also known as PLSCR3 Rabbit mAb. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLSCR3. It may not necessarily be applicable to this product.

NCBI GI #

320118922

NCBI GeneID

57048

NCBI Accession #

NP_001188505.1

UniProt Primary Accession #

Q9NRY6

UniProt Secondary Accession #

Q567U0; Q8NBW6; Q96F13; A8K252

UniProt Related Accession #

Q9NRY6

GenBank Nucleotide #

NM_001201576.1

NCBI Official Full Name

phospholipid scramblase 3

NCBI Official Synonym Full Names

phospholipid scramblase 3

NCBI Official Symbol

PLSCR3

UniProt Protein Name

Phospholipid scramblase 3

UniProt Synonym Protein Names

Ca(2+)-dependent phospholipid scramblase 3

Protein Family

Phospholipid scramblase

UniProt Gene Name

PLSCR3

UniProt Synonym Gene Names

PL scramblase 3

UniProt Entry Name

PLS3_HUMAN

NCBI Protein Information

phospholipid scramblase 3; PL scramblase 3; ca(2+)-dependent phospholipid scramblase 3

UniProt Comments for PLSCR3

PLSCR3: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: mitochondrial membrane; integral to membrane; plasma membrane

Molecular Function: phospholipid scramblase activity; protein binding; calcium ion binding; calcium-dependent protein binding; SH3 domain binding

Biological Process: cholesterol homeostasis; apoptosis; phospholipid scrambling; glucose homeostasis

Research Articles on PLSCR3

1. Secreted Scr3 was taken up by HeLa cells, suggesting that Scr3 functions as a cell-to-cell transferable modulator carried by exosomes in a paracrine manner.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLSCR3 antibody

Reference Product	PubMed Publications
PDCD6 antibody	>3 publications with PLSCR3 and PDCD6

Diseases associated with anti-PLSCR3 antibody

Disease Name	Pubmed Publications
Death Antibodies	>4 publications with PLSCR3 and Death
Brain Ischemia Antibodies	>3 publications with PLSCR3 and Brain Ischemia
Cardiovascular Diseases Antibodies	>3 publications with PLSCR3 and Cardiovascular Diseases
Inflammation Antibodies	>2 publications with PLSCR3 and Inflammation
Necrosis Antibodies	>2 publications with PLSCR3 and Necrosis
Disease Models, Animal Antibodies	>1 publications with PLSCR3 and Disease Models, Animal
Nerve Degeneration Antibodies	>1 publications with PLSCR3 and Nerve Degeneration
Heart Diseases Antibodies	>1 publications with PLSCR3 and Heart Diseases
Atrophy Antibodies	>1 publications with PLSCR3 and Atrophy

Organs/Tissues associated with anti-PLSCR3 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with PLSCR3 and Brain
Muscle Antibodies	>2 publications with PLSCR3 and Muscle
Connective Tissue Antibodies	>2 publications with PLSCR3 and Connective Tissue
Nerve Antibodies	>1 publications with PLSCR3 and Nerve
Blood Antibodies	>1 publications with PLSCR3 and Blood
Vascular Antibodies	>1 publications with PLSCR3 and Vascular
Heart Antibodies	>1 publications with PLSCR3 and Heart
Bone Marrow Antibodies	>1 publications with PLSCR3 and Bone Marrow
Spleen Antibodies	>1 publications with PLSCR3 and Spleen
Kidney Antibodies	>1 publications with PLSCR3 and Kidney