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S100A10 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS475582

Entrez Summary: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a… More details

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Product Overview

Online Datasheet in PDF
Product Name
S100A10, Monoclonal Antibody
Full Product Name
Anti-S100A10 Mouse mAb
Product Gene Name
anti-S100A10 antibody
Product Synonym Gene Name
S100A10; 42C; ANX2L; ANX2LG; CAL1L; CLP11; Ca[1]; GP11; P11; p10
Product Synonym Names
42C; AA409961; AL024248; Annexin II ligand; Annexin II ligand, calpactin I, light polypeptide; Annexin II, light chain; ANX2L; ANX2LG; Ca[1]; CAL12; CAL1L; Calpactin I light chain; Calpactin I, p11 subunit; Calpactin-1 light chain; Cellular ligand of annexin II; CLP11; GP11; MGC111133; Nerve growth factor-induced protein 42C; OTTHUMP00000015269; OTTHUMP00000015270; p10; p10 protein; p11; Protein S100 A10; Protein S100-A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium binding protein A10 (calpactin); S100 calcium binding protein A10; S100 calcium-binding protein A10; S100a10; S10AA_HUMAN
Clonality
Monoclonal
Isotype
lgG2a
Clone Number
6F4-E6-D5-C10
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Sensitivity
This antibody detects endogenous levels of S100A10 and does not cross-react with other S100 family proteins.
Form/Format
Purified mouse monoclonal antibody in PBS (pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Purity/Purification
Affinity Purified
Concentration
4.38mg/ml (lot specific)
Molecular Weight
11kDa
3D Structure
ModBase 3D Structure for P08207
Immunogen
Purified recombinant human S100A10 protein fragments expressed in E Coli.
Sequence Similarities
Belongs to the S-100 family
Subunit Structure
Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A.
Subcellular Location
extracellular exosome; extrinsic component of plasma membrane; membrane raft
Applications Tested/Suitable for anti-S100A10 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
Application Notes for anti-S100A10 antibody
WB: 1:1000
ICC: 1:200
IP: 1:100

Western Blot (WB) of anti-S100A10 antibody

Western blot detection of S100A10 in C6, 3T3 and Hela cell lysates using S100A10 mouse mAb (1:1000 diluted).Predicted band size:11KDa.Observed band size:11KDa.
Mouse Anti-S100A10 Monoclonal Antibody – Cat# MBS475582

Immunocytochemistry (ICC) of anti-S100A10 antibody

Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-S100A10 mouse mAb (dilution 1:200).
Mouse Anti-S100A10 Monoclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS475582

Immunoprecipitation (IP) of anti-S100A10 antibody

Immunoprecipitation analysis of Hela cell lysates using S100A10 mouse mAb.
Mouse Anti-S100A10 Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS475582

Other Notes

Small volumes of anti-S100A10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for S100A10 purchase

MBS475582 is an antibody targeting S100A10. Also known as Anti-S100A10 Mouse mAb. Reactive in Human, Mouse, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for S100A10. It may not necessarily be applicable to this product.

NCBI GI #
6677833
NCBI GeneID
20194
NCBI Accession #
NP_033138.1
UniProt Primary Accession #
P08207
UniProt Related Accession #
P08207
GenBank Nucleotide #
NM_002966
NCBI Official Full Name
protein S100-A10
NCBI Official Synonym Full Names
S100 calcium binding protein A10 (calpactin)
NCBI Official Symbol
S100a10
NCBI Official Synonym Symbols
42C; p10; p11; CAL12; CLP11; Cal1l; AA409961; AL024248
UniProt Protein Name
Protein S100-A10
UniProt Synonym Protein Names
Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
Protein Family
Protein
UniProt Gene Name
S100a10
UniProt Synonym Gene Names
Cal1l
NCBI Protein Information
protein S100-A10

UniProt Comments for S100A10

S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 3 F2.1|3 40.51 cM

Cellular Component: endoplasmic reticulum; extrinsic to plasma membrane; lipid raft

Molecular Function: protein homodimerization activity

Biological Process: lipid raft formation; membrane budding; positive regulation of binding; positive regulation of focal adhesion formation; positive regulation of GTPase activity; positive regulation of stress fiber formation; protein heterotetramerization
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Research Articles on S100A10

1. p11 might be a potential regulator on 5-HTR1b and 5-HTR4 as well as a predictor of or a therapeutic target for IFN-alpha-induced depression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-S100A10 antibody

 Reference Product  PubMed Publications
 Anxa2 antibody  >152 publications with S100A10 and Anxa2
 S100a6 antibody  >23 publications with S100A10 and S100a6
 Cftr antibody  >4 publications with S100A10 and Cftr
 Anxa1 antibody  >3 publications with S100A10 and Anxa1
 Plg antibody  >3 publications with S100A10 and Plg
 Trpv6 antibody  >3 publications with S100A10 and Trpv6
 Dlc1 antibody  >1 publications with S100A10 and Dlc1

Pathways associated with anti-S100A10 antibody

 Products by Pathway  Pathway Diagram
 Dissolution Of Fibrin Clot Pathway antibodies  Dissolution Of Fibrin Clot Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram

Diseases associated with anti-S100A10 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >27 publications with S100A10 and Inflammation
 Carcinoma Antibodies  >18 publications with S100A10 and Carcinoma
 Disease Models, Animal Antibodies  >11 publications with S100A10 and Disease Models, Animal
 Necrosis Antibodies  >10 publications with S100A10 and Necrosis
 Nervous System Diseases Antibodies  >10 publications with S100A10 and Nervous System Diseases
 Brain Diseases Antibodies  >8 publications with S100A10 and Brain Diseases
 Depressive Disorder Antibodies  >8 publications with S100A10 and Depressive Disorder
 Breast Neoplasms Antibodies  >7 publications with S100A10 and Breast Neoplasms
 Leukemia, Myeloid, Acute Antibodies  >5 publications with S100A10 and Leukemia, Myeloid, Acute
 Neoplasm Metastasis Antibodies  >5 publications with S100A10 and Neoplasm Metastasis

Organs/Tissues associated with anti-S100A10 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >29 publications with S100A10 and Brain
 Blood Antibodies  >26 publications with S100A10 and Blood
 Skin Antibodies  >11 publications with S100A10 and Skin
 Kidney Antibodies  >10 publications with S100A10 and Kidney
 Muscle Antibodies  >8 publications with S100A10 and Muscle
 Lung Antibodies  >7 publications with S100A10 and Lung
 Intestine Antibodies  >6 publications with S100A10 and Intestine
 Liver Antibodies  >5 publications with S100A10 and Liver
 Connective Tissue Antibodies  >4 publications with S100A10 and Connective Tissue
 Ovary Antibodies  >4 publications with S100A10 and Ovary
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