Albumin (ALB) Antibody – Mouse Monoclonal

This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016]

albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carrier; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: endoplasmic reticulum; extracellular region; extracellular space; Golgi apparatus; nucleus; protein complex

Molecular Function: chaperone binding; DNA binding; drug binding; fatty acid binding; identical protein binding; oxygen binding; protein binding; pyridoxal phosphate binding; toxin binding

Biological Process: bile acid and bile salt transport; cellular response to starvation; hemolysis by symbiont of host red blood cells; lipoprotein metabolic process; maintenance of mitochondrion localization; negative regulation of apoptosis; platelet degranulation; receptor-mediated endocytosis; retinal homeostasis; sodium-independent organic anion transport; transport

Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic