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RTN3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS475929

Entrez Summary: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid… More details

$525 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RTN3, Monoclonal Antibody
Full Product Name
Anti-RTN3 Mouse mAb
Product Gene Name
Product Synonym Gene Name
HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
Product Synonym Names
HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
10A8
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Molecular Weight
113
3D Structure
ModBase 3D Structure for Q9ES97
Immunogen
Purified recombinant fragment of RTN3 expressed in E Coli.
Applications Tested/Suitable for anti-RTN3 antibody
Immunohistochemistry (IHC)

Immunohistochemistry (IHC) of anti-RTN3 antibody

Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and breast cancer (right) using RTN3 mouse mAb with DAB staining.
Mouse Anti-RTN3 Monoclonal Antibody – Cat# MBS475929

Immunohistochemistry (IHC) of anti-RTN3 antibody

Immunohistochemical analysis of paraffin-embedded human Liver tissues using RTN3 mouse mAb
Mouse Anti-RTN3 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS475929

Other Notes

Small volumes of anti-RTN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RTN3 purchase

MBS475929 is an antibody targeting RTN3. Also known as Anti-RTN3 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for RTN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
reticulon-3 isoform 6
NCBI Official Synonym Full Names
reticulon 3
NCBI Official Symbol
Rtn3
NCBI Official Synonym Symbols
RTN3-A1
UniProt Protein Name
Reticulon-3
Protein Family
UniProt Gene Name
Rtn3
NCBI Protein Information
reticulon-3

UniProt Comments for RTN3

RTN3: May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19|19 A

Cellular Component: endomembrane system; endoplasmic reticulum; endoplasmic reticulum membrane

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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