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BDH1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS475977

Entrez Summary: BDH1 (3-hydroxybutyrate dehydrogenase, type 1), it is a member of the short-chain dehydrogenase/reductase gene family. This protien forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for… More details

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Product Overview

Online Datasheet in PDF
Product Name
BDH1, Monoclonal Antibody
Full Product Name
Anti-BDH1 Mouse mAb
Product Gene Name
anti-BDH1 antibody
Product Synonym Gene Name
BDH
Product Synonym Names
BDH
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1A5
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Molecular Weight
38
OMIM
M93107 mRNA
Immunogen
Purified recombinant fragment of human BDH1 expressed in E Coli.
Applications Tested/Suitable for anti-BDH1 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-BDH1 antibody

Western blot analysis using BDH1 mouse mAb against HepG2 (1) and NIH/3T3 (2) cell lysate.
Mouse Anti-BDH1 Monoclonal Antibody – Cat# MBS475977

Immunohistochemistry (IHC) of anti-BDH1 antibody

Immunohistochemical analysis of paraffin-embedded human Prostate tissues using anti-BDH1 mouse mAb
Mouse Anti-BDH1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS475977

Immunohistochemistry (IHC) of anti-BDH1 antibody

Immunohistochemical analysis of paraffin-embedded human liver cancer (left) and colorectal cancer tissues (right) using BDH1 mouse mAb with DAB staining.
Mouse Anti-BDH1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS475977

Other Notes

Small volumes of anti-BDH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BDH1 purchase

MBS475977 is an antibody targeting BDH1. Also known as Anti-BDH1 Mouse mAb. Reactive in Human, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for BDH1. It may not necessarily be applicable to this product.

NCBI GI #
906316404
NCBI GeneID
622
NCBI Accession #
CEP24661.1
UniProt Secondary Accession #
Q96ET1; Q9BRZ4; D3DXC0
UniProt Related Accession #
Q02338
NCBI Official Full Name
BDH1
NCBI Official Synonym Full Names
3-hydroxybutyrate dehydrogenase 1
NCBI Official Symbol
BDH1
NCBI Official Synonym Symbols
BDH; SDR9C1
UniProt Protein Name
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
UniProt Synonym Protein Names
3-hydroxybutyrate dehydrogenase
Protein Family
(R,R)-butanediol dehydrogenase
UniProt Gene Name
BDH1
UniProt Synonym Gene Names
BDH
NCBI Protein Information
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

NCBI Summary for BDH1

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for BDH1

BDH: a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Protein type: Carbohydrate Metabolism - butanoate; EC 1.1.1.30; Lipid Metabolism - synthesis and degradation of ketone bodies; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: cytoplasm; mitochondrial matrix; mitochondrion; nucleoplasm

Molecular Function: 3-hydroxybutyrate dehydrogenase activity

Biological Process: ketone body biosynthetic process; ketone body catabolic process
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Research Articles on BDH1

1. Data show that the ketone body metabolizing enzymes BDH1, BDH2, OXCT1 and ACAT1 were expressed at the mRNA and protein level in all glioma cell lines.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BDH1 antibody

 Reference Product  PubMed Publications
 BDH2 antibody  >8 publications with BDH1 and BDH2
 ACAT1 antibody  >6 publications with BDH1 and ACAT1
 HMGCL antibody  >4 publications with BDH1 and HMGCL
 OXCT1 antibody  >4 publications with BDH1 and OXCT1

Pathways associated with anti-BDH1 antibody

 Products by Pathway  Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Ketone Body Metabolism Pathway antibodies  Ketone Body Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Synthesis And Degradation Of Ketone Bodies Pathway antibodies  Synthesis And Degradation Of Ketone Bodies Pathway Diagram
 Synthesis And Degradation Of Ketone Bodies Pathway antibodies  Synthesis And Degradation Of Ketone Bodies Pathway Diagram

Diseases associated with anti-BDH1 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >4 publications with BDH1 and Fatty Liver
 Inflammation Antibodies  >3 publications with BDH1 and Inflammation
 Heart Diseases Antibodies  >1 publications with BDH1 and Heart Diseases
 Neoplasm Metastasis Antibodies  >1 publications with BDH1 and Neoplasm Metastasis
 Liver Diseases Antibodies  >1 publications with BDH1 and Liver Diseases
 Weight Loss Antibodies  >1 publications with BDH1 and Weight Loss

Organs/Tissues associated with anti-BDH1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with BDH1 and Blood
 Liver Antibodies  >5 publications with BDH1 and Liver
 Muscle Antibodies  >4 publications with BDH1 and Muscle
 Heart Antibodies  >4 publications with BDH1 and Heart
 Brain Antibodies  >3 publications with BDH1 and Brain
 Adipose Tissue Antibodies  >2 publications with BDH1 and Adipose Tissue
 Prostate Antibodies  >1 publications with BDH1 and Prostate
 Mammary Gland Antibodies  >1 publications with BDH1 and Mammary Gland
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