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MSI2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS476142

Entrez Summary: Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MSI2, Monoclonal Antibody
Full Product Name
Anti-MSI2 Mouse mAb
Product Gene Name
Product Synonym Gene Name
MSI2H; MGC3245; FLJ36569; MSI2
Product Synonym Names
MSI2H; MGC3245; FLJ36569; MSI2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2C11
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Molecular Weight
35
OMIM
BC001526 mRNA
Immunogen
Purified recombinant fragment of human MSI2 expressed in E Coli.
Applications Tested/Suitable for anti-MSI2 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-MSI2 antibody

Western blot analysis using MSI2 mouse mAb against NTERA-2 (1), SW620 (2) and T47D (3) cell lysate.
Mouse Anti-MSI2 Monoclonal Antibody – Cat# MBS476142

Immunohistochemistry (IHC) of anti-MSI2 antibody

Immunohistochemical analysis of paraffin-embedded ovarian cancer (left) and cerebellum tissues (right) using MSI2 mouse mAb with DAB staining.
Mouse Anti-MSI2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS476142

Other Notes

Small volumes of anti-MSI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MSI2 purchase

MBS476142 is an antibody targeting MSI2. Also known as Anti-MSI2 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MSI2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
MSI2 protein
NCBI Official Synonym Full Names
musashi RNA binding protein 2
NCBI Official Symbol
MSI2
NCBI Official Synonym Symbols
MSI2H
UniProt Protein Name
RNA-binding protein Musashi homolog 2
Protein Family
UniProt Gene Name
MSI2
UniProt Synonym Gene Names
Musashi-2
NCBI Protein Information
RNA-binding protein Musashi homolog 2

NCBI Summary for MSI2

This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
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UniProt Comments for MSI2

Musashi-2: RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23). Belongs to the Musashi family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 17q22

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MSI2 antibody

 Reference Product  PubMed Publications
 NUMB antibody  >14 publications with MSI2 and NUMB

Pathways associated with anti-MSI2 antibody

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