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Glycogen Synthase 1 (GYS1) Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4761599

Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Allosteric activation by glucose-6-phosphate. Phosphorylation reduces the activity towards UDP-glucose. When in the non-phosphorylated state, glycogen synthase does not… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glycogen Synthase 1 (GYS1), Monoclonal Antibody
Full Product Name
Glycogen Synthase 1 Rabbit mAb
Product Gene Name
Product Synonym Names
GYS1; GYS; Glycogen [starch] synthase; muscle
Clonality
Monoclonal
Isotype
IgG
Clone Number
R09-1E5
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purity/Purification
Affinity Purified
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
Molecular Weight
83,786 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (49471382..49496610, complement). Location: 19q13.3
OMIM
138570
3D Structure
ModBase 3D Structure for P13807
Immunogen
A synthetic peptide of human Glycogen synthase 1
Conjugation
Unconjugated
Modification
Unmodified
Research Area
Signal Transduction
Applications Tested/Suitable for anti-GYS1 antibody
Western Blot (WB), Immunohistochemistry-Frozen (IHC-F), Immunohistochemistry-Paraffin (IHC-P), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
Application Notes for anti-GYS1 antibody
WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
IP: 1/20

Western Blot (WB) of anti-GYS1 antibody

Western blot analysis of Glycogen synthase 1 in Hela lysates using Glycogen Synthase 1 antibody.
Rabbit Anti-GYS1 Monoclonal Antibody – Cat# MBS4761599

Other Notes

Small volumes of anti-GYS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GYS1 purchase

MBS4761599 is an antibody targeting GYS1. Also known as Glycogen Synthase 1 Rabbit mAb. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GYS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glycogen
NCBI Official Synonym Full Names
glycogen synthase 1 (muscle)
NCBI Official Symbol
GYS1
NCBI Official Synonym Symbols
GSY; GYS
UniProt Protein Name
Glycogen [starch] synthase, muscle
UniProt Gene Name
GYS1
UniProt Synonym Gene Names
GYS
UniProt Entry Name
GYS1_HUMAN
NCBI Protein Information
glycogen [starch] synthase, muscle; glycogen [starch] synthase, muscle

NCBI Summary for GYS1

The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
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UniProt Comments for GYS1

GYS1: muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation.

Protein type: EC 2.4.1.11; Transferase; Carbohydrate Metabolism - starch and sucrose

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: membrane; cytoplasm; inclusion body; cytosol

Molecular Function: protein binding; glycogen (starch) synthase activity; protein kinase binding; glucose binding

Biological Process: glycogen biosynthetic process; heart development; carbohydrate metabolic process; glucose metabolic process; pathogenesis

Disease: Glycogen Storage Disease 0, Muscle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GYS1 antibody

 Reference Product  PubMed Publications
 GSK3B antibody  >1 publications with GYS1 and GSK3B
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