Delta Opioid Receptor (OPRD1) Antibody – Rabbit Monoclonal

DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.1-p34.3

Cellular Component: postsynaptic membrane; neuron projection; integral to plasma membrane; cytoplasm; plasma membrane; nerve terminal; intrinsic to plasma membrane; vesicle; lipid raft

Molecular Function: neuropeptide binding; protein binding; opioid receptor activity

Biological Process: adult locomotory behavior; activation of CREB transcription factor; regulation of calcium ion transport; sensory perception of pain; positive regulation of peptidyl-serine phosphorylation; G-protein coupled receptor protein signaling pathway; negative regulation of protein oligomerization; synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; regulation of mitochondrial membrane potential; neuropeptide signaling pathway; protein import into nucleus, translocation; immune response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); regulation of sensory perception of pain; G-protein signaling, adenylate cyclase inhibiting pathway