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CPEB1 Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4763392

Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an… More details

$525 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
CPEB1, Monoclonal Antibody
Full Product Name
CPEB1 Rabbit mAb
Product Gene Name
Product Synonym Names
CEBP; CPE-BP1; CPEB1; h CEBP; hCPEB 1
Clonality
Monoclonal
Isotype
IgG
Clone Number
R09-1V4
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity Purified
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
Molecular Weight
53,635 Da
OMIM
607342
3D Structure
ModBase 3D Structure for Q9BZB8
Immunogen
A synthesized peptide derived from human CPEB1
Conjugation
Unconjugated
Modification
Unmodified
Research Area
-
Applications Tested/Suitable for anti-CPEB1 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-CPEB1 antibody
WB: 1/500-1/1000
IP: 1/50

Western Blot (WB) of anti-CPEB1 antibody

Western blot analysis of CPEB1 in A549 lysates using CPEB1 antibody.
Rabbit Anti-CPEB1 Monoclonal Antibody – Cat# MBS4763392

Other Notes

Small volumes of anti-CPEB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CPEB1 purchase

MBS4763392 is an antibody targeting CPEB1. Also known as CPEB1 Rabbit mAb. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CPEB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Cytoplasmic polyadenylation element-binding protein 1
NCBI Official Synonym Full Names
cytoplasmic polyadenylation element binding protein 1
NCBI Official Symbol
CPEB1
NCBI Official Synonym Symbols
CPEB; CPEB-1; CPE-BP1; hCPEB-1
UniProt Protein Name
Cytoplasmic polyadenylation element-binding protein 1
UniProt Gene Name
CPEB1
UniProt Synonym Gene Names
CPEB; CPE-BP1; CPE-binding protein 1; h-CEBP; hCPEB-1
UniProt Entry Name
CPEB1_HUMAN
NCBI Protein Information
cytoplasmic polyadenylation element-binding protein 1; CPE-binding protein 1

NCBI Summary for CPEB1

This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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UniProt Comments for CPEB1

CPEB: cytoplasmic polyadenylation element binding protein 1. Binds to the protein CPE and drives its polyadenylation. Activated by the protein kinase AurA. Insulin and progesterone stimulate AurA-catalyzed phosphorylation of CPEB in oocytes. Neuronal CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia.

Protein type: Translation; RNA-binding

Chromosomal Location of Human Ortholog: 15q25.2

Cellular Component: postsynaptic membrane; dendrite; postsynaptic density; cytoplasm; nucleus; cell junction

Molecular Function: metal ion binding; translation repressor activity, nucleic acid binding; nucleotide binding

Biological Process: synaptonemal complex assembly; cellular response to insulin stimulus; mRNA processing; regulation of neuronal synaptic plasticity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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