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BCL2L12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9406449

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor… More details

$260 / 0.05 mL +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BCL2L12, Polyclonal Antibody
Full Product Name
BCL2L12 Antibody
Product Gene Name
Product Synonym Names
Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1.0 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total BCL2L12 protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
36,665 Da
OMIM
610837
3D Structure
ModBase 3D Structure for Q9HB09
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human BCL2L12.
Target Name
BCL2L12

Product Categories/Family for anti-BCL2L12 antibody

Applications Tested/Suitable for anti-BCL2L12 antibody
Western Blot (WB)
Application Notes for anti-BCL2L12 antibody
Western blotting: 1:500~1:3000

Western Blot (WB) of anti-BCL2L12 antibody

Western blot analysis of extracts from CoLo cells, using BCL2L12 antibody.
Rabbit Anti-BCL2L12 Polyclonal Antibody – Cat# MBS9406449

Other Notes

Small volumes of anti-BCL2L12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCL2L12 purchase

MBS9406449 is an antibody targeting BCL2L12. Also known as BCL2L12 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BCL2L12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bcl-2-like protein 12 isoform 3
NCBI Official Synonym Full Names
BCL2-like 12 (proline rich)
NCBI Official Symbol
BCL2L12
UniProt Protein Name
Bcl-2-like protein 12
UniProt Synonym Protein Names
Bcl-2-related proline-rich protein
Protein Family
UniProt Gene Name
BCL2L12
UniProt Synonym Gene Names
BPR; Bcl2-L-12
UniProt Entry Name
B2L12_HUMAN
NCBI Protein Information
bcl-2-like protein 12

NCBI Summary for BCL2L12

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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UniProt Comments for BCL2L12

Bcl-2L12: belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: membrane; nucleus

Molecular Function: protein binding; p53 binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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