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Dynein Light Chain (DNAL4) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS476401

Entrez Summary: This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is… More details

$525 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Dynein light chain (DNAL4), Monoclonal Antibody
Full Product Name
Anti-Dynein light chain Mouse mAb
Product Gene Name
Product Synonym Gene Name
MRMV3; PIG27
Product Synonym Names
D15Ertd424e; Dnal4; DNAL4_HUMAN; Dnalc4; Dynein axonemal light chain 4; Dynein light chain 4, axonemal; Dynein light chain, outer arm 4; Dynein, axonemal, light 4; Dynein, axonemal, light polypeptide 4; MGC105573; PIG27; Proliferation inducing gene 27; Proliferation inducing protein 27
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4D12-C10-D5
Host
Mouse
Species Reactivity
Rat
Form/Format
Purified antibody in PBS with 0.05% sodium azide.
Molecular Weight
12kDa
OMIM
AL035366 mRNA
3D Structure
ModBase 3D Structure for O96015
Immunogen
Purified recombinant fragment of human DNAL4 (AA: 1-105) expressed in E Coli.
Sequence Similarities
Belongs to the dynein light chain family.
Subunit Structure
Consists of at least two heavy chains and a number of intermediate and light chains.
Subcellular Location
Cytoplasm; Cytoskeleton; Cilium axoneme
Applications Tested/Suitable for anti-DNAL4 antibody
Western Blot (WB)

Western Blot (WB) of anti-DNAL4 antibody

Western blot analysis of extracts from C6 cell lysates using Dynein light chain mouse mAb (1:500 diluted).Predicted band size:12KDa.Observed band size:12KDa.
Mouse Anti-DNAL4 Monoclonal Antibody – Cat# MBS476401

Other Notes

Small volumes of anti-DNAL4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNAL4 purchase

MBS476401 is an antibody targeting DNAL4. Also known as Anti-Dynein light chain Mouse mAb. Reactive in Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAL4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dynein light chain 4, axonemal
NCBI Official Synonym Full Names
dynein axonemal light chain 4
NCBI Official Symbol
DNAL4
NCBI Official Synonym Symbols
MRMV3; PIG27
UniProt Protein Name
Dynein light chain 4, axonemal
Protein Family
UniProt Gene Name
DNAL4
NCBI Protein Information
dynein light chain 4, axonemal

NCBI Summary for DNAL4

This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014]
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UniProt Comments for DNAL4

DNAL4: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity. Belongs to the dynein light chain family.

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: plasma membrane

Molecular Function: microtubule motor activity; protein binding

Biological Process: microtubule-based movement

Disease: Mirror Movements 3
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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