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NKX6-1 Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4764194

Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (By similarity). More details

$525 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NKX6.1 (NKX6-1), Monoclonal Antibody
Full Product Name
NKX6.1 Rabbit mAb
Product Gene Name
Product Synonym Gene Name
NKX6.1
Product Synonym Names
NKX6-1; NKX6A; Homeobox protein Nkx-6.1; Homeobox protein NK-6 homolog A
Clonality
Monoclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.275.
Purity/Purification
Affinity Purified
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
Molecular Weight
37,849 Da
3D Structure
ModBase 3D Structure for P78426
Immunogen
Recombinant protein of human NKX6.1
Conjugation
Unconjugated
Modification
Unmodified
Research Area
Epigenetics and Nuclear Signaling
Applications Tested/Suitable for anti-NKX6-1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes for anti-NKX6-1 antibody
IHC: 1/100-1/200

Other Notes

Small volumes of anti-NKX6-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NKX6-1 purchase

MBS4764194 is an antibody targeting NKX6-1. Also known as NKX6.1 Rabbit mAb. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NKX6-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein Nkx-6.1
NCBI Official Synonym Full Names
NK6 homeobox 1
NCBI Official Symbol
NKX6-1
NCBI Official Synonym Symbols
NKX6A; NKX6.1
UniProt Protein Name
Homeobox protein Nkx-6.1
UniProt Synonym Protein Names
Homeobox protein NK-6 homolog A
Protein Family
UniProt Gene Name
NKX6-1
UniProt Synonym Gene Names
NKX6A
NCBI Protein Information
homeobox protein Nkx-6.1

NCBI Summary for NKX6-1

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008]

UniProt Comments for NKX6-1

Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-NKX6-1 antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >227 publications with NKX6-1 and Pancreas
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