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DSG3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS476533

Entrez Summary: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein… More details

$525 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DSG3, Monoclonal Antibody
Full Product Name
Anti-DSG3 Mouse mAb
Product Gene Name
Product Synonym Gene Name
PVA; CDHF6
Product Synonym Names
PVA; CDHF6
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6G2C11
Host
Mouse
Species Reactivity
Human
Form/Format
Purified antibody in PBS with 0.05% sodium azide.
Molecular Weight
107.5
OMIM
M76482 mRNA
3D Structure
ModBase 3D Structure for P32926
Immunogen
Purified recombinant fragment of human DSG3 (AA: 55-159) expressed in E Coli.
Applications Tested/Suitable for anti-DSG3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Western Blot (WB) of anti-DSG3 antibody

Western blot analysis using DSG3 mAb against human DSG3 (AA
Mouse Anti-DSG3 Monoclonal Antibody – Cat# MBS476533

Western Blot (WB) of anti-DSG3 antibody

Western blot analysis using DSG3 mAb against HEK293 (1) and DSG3 (AA
Mouse Anti-DSG3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS476533

Western Blot (WB) of anti-DSG3 antibody

Western blot analysis using DSG3 mouse mAb against A431 cell lysate.
Mouse Anti-DSG3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS476533

Flow Cytometry (FC/FACS) of anti-DSG3 antibody

Flow cytometric analysis of A431 cells using DSG3 mouse mAb (green) and negative control (red).
Mouse Anti-DSG3 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS476533

Immunohistochemistry (IHC) of anti-DSG3 antibody

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using DSG3 mouse mAb with DAB staining.
Mouse Anti-DSG3 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS476533

Immunohistochemistry (IHC) of anti-DSG3 antibody

Immunohistochemical analysis of paraffin-embedded esophageal tissues using DSG3 mouse mAb with DAB staining.
Mouse Anti-DSG3 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS476533

Other Notes

Small volumes of anti-DSG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DSG3 purchase

MBS476533 is an antibody targeting DSG3. Also known as Anti-DSG3 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DSG3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
desmoglein-3 preproprotein
NCBI Official Synonym Full Names
desmoglein 3
NCBI Official Symbol
DSG3
NCBI Official Synonym Symbols
PVA; CDHF6
UniProt Protein Name
Desmoglein-3
UniProt Synonym Protein Names
130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6
Protein Family
UniProt Gene Name
DSG3
UniProt Synonym Gene Names
CDHF6; PVA
NCBI Protein Information
desmoglein-3

NCBI Summary for DSG3

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
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UniProt Comments for DSG3

DSG3: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q12.1

Cellular Component: cytosol; plasma membrane
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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