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MMEL1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS476553

Entrez Summary: The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and… More details

$525 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MMEL1, Monoclonal Antibody
Full Product Name
Anti-MMEL1 Mouse mAb
Product Gene Name
Product Synonym Gene Name
NL1; NL2; SEP; NEP2; MMEL2; NEPII
Product Synonym Names
NL1; NL2; SEP; NEP2; MMEL2; NEPII
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2D2H5
Host
Mouse
Species Reactivity
Human
Form/Format
Purified antibody in PBS with 0.05% sodium azide.
Molecular Weight
89.4
3D Structure
ModBase 3D Structure for Q495T6
Immunogen
Purified recombinant fragment of human MMEL1 (AA: 1-107) expressed in E Coli.
Applications Tested/Suitable for anti-MMEL1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Western Blot (WB) of anti-MMEL1 antibody

Western blot analysis using MMEL1 mAb against human MMEL1 (AA
Mouse Anti-MMEL1 Monoclonal Antibody – Cat# MBS476553

Western Blot (WB) of anti-MMEL1 antibody

Western blot analysis using MMEL1 mAb against HEK293 (1) and MMEL1 (AA
Mouse Anti-MMEL1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS476553

Flow Cytometry (FC/FACS) of anti-MMEL1 antibody

Flow cytometric analysis of Hela cells using MMEL1 mouse mAb (green) and negative control (red).
Mouse Anti-MMEL1 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS476553

Immunohistochemistry (IHC) of anti-MMEL1 antibody

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using MMEL1 mouse mAb with DAB staining.
Mouse Anti-MMEL1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS476553

Immunohistochemistry (IHC) of anti-MMEL1 antibody

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MMEL1 mouse mAb with DAB staining.
Mouse Anti-MMEL1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS476553

Other Notes

Small volumes of anti-MMEL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MMEL1 purchase

MBS476553 is an antibody targeting MMEL1. Also known as Anti-MMEL1 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MMEL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
membrane metallo-endopeptidase-like 1
NCBI Official Synonym Full Names
membrane metalloendopeptidase like 1
NCBI Official Symbol
MMEL1
NCBI Official Synonym Symbols
NL1; NL2; SEP; NEP2; MMEL2; NEPII
UniProt Protein Name
Membrane metallo-endopeptidase-like 1
UniProt Synonym Protein Names
Membrane metallo-endopeptidase-like 2; NEP2(m); Neprilysin II; NEPII
UniProt Gene Name
MMEL1
UniProt Synonym Gene Names
MELL1; MMEL2; NEP2; NEPII; NEP2; NL2; NEP2(s)
NCBI Protein Information
membrane metallo-endopeptidase-like 1

NCBI Summary for MMEL1

The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008]
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UniProt Comments for MMEL1

MELL1: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond. Belongs to the peptidase M13 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.24.11; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 1p36.32
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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