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PRMT6 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS476622

Entrez Summary: Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Product Name
PRMT6, Monoclonal Antibody
Full Product Name
Anti-PRMT6 Mouse mAb
Product Gene Name
Product Synonym Names
GIG13
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4B9D7
Host
Mouse
Species Reactivity
Human, Monkey
Form/Format
Purified antibody in PBS with 0.05% sodium azide.
Molecular Weight
42
OMIM
AB047521 Genomic DNA
Immunogen
Purified recombinant fragment of human PER3 (AA: 723-954) expressed in E Coli.
Applications Tested/Suitable for anti-PRMT6 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Western Blot (WB) of anti-PRMT6 antibody

Western blot analysis using PRMT6 mouse mAb against A431 (1), Hela (2), A549 (3) and HEK293 (4) cell lysate.
Mouse Anti-PRMT6 Monoclonal Antibody – Cat# MBS476622

Other Notes

Small volumes of anti-PRMT6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRMT6 purchase

MBS476622 is an antibody targeting PRMT6. Also known as Anti-PRMT6 Mouse mAb. Reactive in Human, Monkey. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PRMT6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Prmt6, partial
NCBI Official Synonym Full Names
period circadian clock 3
NCBI Official Symbol
PER3
NCBI Official Synonym Symbols
GIG13; FASPS3
UniProt Protein Name
Period circadian protein homolog 3
UniProt Synonym Protein Names
Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3
UniProt Gene Name
PER3
UniProt Synonym Gene Names
hPER3
NCBI Protein Information
period circadian protein homolog 3

NCBI Summary for PRMT6

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]
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UniProt Comments for PRMT6

PER3: Component of the circadian clock mechanism which is essential for generating circadian rhythms. Can bind heme. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 1p36.23

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: negative regulation of transcription from RNA polymerase II promoter; protein stabilization; regulation of circadian sleep/wake cycle, sleep

Disease: Advanced Sleep Phase Syndrome, Familial, 3
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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