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CLGN Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS476671

Entrez Summary: Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CLGN, Monoclonal Antibody
Full Product Name
Anti-CLGN Mouse mAb
Product Gene Name
anti-CLGN antibody
Product Synonym Names
CCNB; CCNB1
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1B10
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Molecular Weight
70
OMIM
D86322 mRNA
3D Structure
ModBase 3D Structure for O14967
Immunogen
Purified recombinant fragment of human CCNB1 expressed in E Coli.
Applications Tested/Suitable for anti-CLGN antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Western Blot (WB) of anti-CLGN antibody

Western blot analysis using CLGN mAb against human CLGN recombinant protein. (Expected MW is 43.5 kDa)
Mouse Anti-CLGN Monoclonal Antibody – Cat# MBS476671

Western Blot (WB) of anti-CLGN antibody

Western blot analysis using CLGN mAb against HEK293 (1) and CLGN (AA
Mouse Anti-CLGN Monoclonal Antibody, Western Blot (WB) – Cat# MBS476671

Western Blot (WB) of anti-CLGN antibody

Western blot analysis using CLGN mouse mAb against LNCaP (1), HepG2 (2), PC-3 (3), and Raji (4) cell lysate.
Mouse Anti-CLGN Monoclonal Antibody, Western Blot (WB) – Cat# MBS476671

Immunofluorescence (IF) of anti-CLGN antibody

Immunofluorescence analysis of HepG2 cells using CLGN mouse mAb (green). Blue
Mouse Anti-CLGN Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS476671

Flow Cytometry (FC/FACS) of anti-CLGN antibody

Flow cytometric analysis of HEK293 cells using CLGN mouse mAb (green) and negative control (purple).
Mouse Anti-CLGN Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS476671

Immunohistochemistry (IHC) of anti-CLGN antibody

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using CLGN mouse mAb with DAB staining.
Mouse Anti-CLGN Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS476671

Immunohistochemistry (IHC) of anti-CLGN antibody

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CLGN mouse mAb with DAB staining.
Mouse Anti-CLGN Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS476671

Other Notes

Small volumes of anti-CLGN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLGN purchase

MBS476671 is an antibody targeting CLGN. Also known as Anti-CLGN Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CLGN. It may not necessarily be applicable to this product.

NCBI GI #
194578888
NCBI GeneID
1047
NCBI Accession #
NP_001124147.1
UniProt Primary Accession #
O14967
UniProt Secondary Accession #
B3KS90; B4DXV8; D3DNY8
UniProt Related Accession #
O14967
GenBank Nucleotide #
NM_001130675.1
NCBI Official Full Name
calmegin
NCBI Official Synonym Full Names
calmegin
NCBI Official Symbol
CLGN
UniProt Protein Name
Calmegin
Protein Family
Calmegin
UniProt Gene Name
CLGN
NCBI Protein Information
calmegin

NCBI Summary for CLGN

Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq, Jul 2008]

UniProt Comments for CLGN

CLGN: Probably plays an important role in spermatogenesis. Binds calcium ions. Belongs to the calreticulin family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q31.1

Cellular Component: endoplasmic reticulum

Biological Process: single fertilization
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Research Articles on CLGN

1. Although their similarity in carbohydrate binding specificities is high, there seems to be some differences in the mode of substrate recognition between calmegin and calnexin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLGN antibody

 Reference Product  PubMed Publications
 ADAM2 antibody  >5 publications with CLGN and ADAM2

Diseases associated with anti-CLGN antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with CLGN and Neoplasms
 Head and Neck Neoplasms Antibodies  >1 publications with CLGN and Head and Neck Neoplasms
 Nervous System Diseases Antibodies  >1 publications with CLGN and Nervous System Diseases
 Thyroid Diseases Antibodies  >1 publications with CLGN and Thyroid Diseases
 Neoplasms, Experimental Antibodies  >1 publications with CLGN and Neoplasms, Experimental
 Gonadal Disorders Antibodies  >1 publications with CLGN and Gonadal Disorders
 Thyroid Neoplasms Antibodies  >1 publications with CLGN and Thyroid Neoplasms
 Ovarian Neoplasms Antibodies  >1 publications with CLGN and Ovarian Neoplasms

Organs/Tissues associated with anti-CLGN antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >8 publications with CLGN and Testis
 Uterus Antibodies  >2 publications with CLGN and Uterus
 Brain Antibodies  >1 publications with CLGN and Brain
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