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CSPG4 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS476690

Entrez Summary: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CSPG4, Monoclonal Antibody
Full Product Name
Anti-CSPG4 Mouse mAb
Product Gene Name
anti-CSPG4 antibody
Product Synonym Names
RAB10
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4E2
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Molecular Weight
250
OMIM
AF086917 mRNA
Immunogen
Purified recombinant fragment of human Rab10 expressed in E Coli.
Applications Tested/Suitable for anti-CSPG4 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Western Blot (WB) of anti-CSPG4 antibody

Western blot analysis using CSPG4 mAb against human CSPG4 recombinant protein. (Expected MW is 32.5 kDa)
Mouse Anti-CSPG4 Monoclonal Antibody – Cat# MBS476690

Western Blot (WB) of anti-CSPG4 antibody

Western blot analysis using CSPG4 mAb against HEK293 (1) and CSPG4 (AA
Mouse Anti-CSPG4 Monoclonal Antibody, Western Blot (WB) – Cat# MBS476690

Flow Cytometry (FC/FACS) of anti-CSPG4 antibody

Flow cytometric analysis of HEK293 cells using CSPG4 mouse mAb (green) and negative control (red).
Mouse Anti-CSPG4 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS476690

Other Notes

Small volumes of anti-CSPG4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSPG4 purchase

MBS476690 is an antibody targeting CSPG4. Also known as Anti-CSPG4 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CSPG4. It may not necessarily be applicable to this product.

NCBI GI #
958937131
NCBI GeneID
10890
NCBI Accession #
JAO98603.1
UniProt Secondary Accession #
O88386; Q6IA52; Q9D7X6; Q9H0T3; D6W538
UniProt Related Accession #
P61026
NCBI Official Full Name
CSPG4, partial
NCBI Official Synonym Full Names
RAB10, member RAS oncogene family
NCBI Official Symbol
RAB10
UniProt Protein Name
Ras-related protein Rab-10
Protein Family
Chondroitin sulfate proteoglycan
UniProt Gene Name
RAB10
NCBI Protein Information
ras-related protein Rab-10

NCBI Summary for CSPG4

RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]

UniProt Comments for CSPG4

RAB10: a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor.

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: cell-cell adherens junction; cilium; cytoplasmic vesicle membrane; endoplasmic reticulum membrane; endosome; exocyst; focal adhesion; Golgi apparatus; intercellular junction; plasma membrane; recycling endosome; trans-Golgi network

Molecular Function: GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding

Biological Process: antigen processing and presentation; axonogenesis; cellular response to insulin stimulus; endosome transport; establishment of neuroblast polarity; Golgi to plasma membrane protein transport; Golgi to plasma membrane transport; polarized epithelial cell differentiation; vesicle-mediated transport
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Research Articles on CSPG4

1. the target gene RAB10 regulated by miRNA-369-3p, miRNA-30e-5p, miRNA-30e-3p, and miRNA-655 may play key role in the progression and development of AD.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CSPG4 antibody

 Reference Product  PubMed Publications
 TBC1D4 antibody  >9 publications with CSPG4 and TBC1D4
 TBC1D1 antibody  >2 publications with CSPG4 and TBC1D1
 EXOC6 antibody  >1 publications with CSPG4 and EXOC6

Pathways associated with anti-CSPG4 antibody

 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Neutrophil Degranulation Pathway antibodies  Neutrophil Degranulation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram

Diseases associated with anti-CSPG4 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with CSPG4 and Nervous System Diseases
 Inflammation Antibodies  >2 publications with CSPG4 and Inflammation
 Infertility, Male Antibodies  >1 publications with CSPG4 and Infertility, Male
 Liver Diseases Antibodies  >1 publications with CSPG4 and Liver Diseases
 Genital Diseases, Male Antibodies  >1 publications with CSPG4 and Genital Diseases, Male
 Liver Neoplasms Antibodies  >1 publications with CSPG4 and Liver Neoplasms
 Edema Antibodies  >1 publications with CSPG4 and Edema
 Disease Models, Animal Antibodies  >1 publications with CSPG4 and Disease Models, Animal
 Weight Loss Antibodies  >1 publications with CSPG4 and Weight Loss
 Carcinoma, Hepatocellular Antibodies  >1 publications with CSPG4 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-CSPG4 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >14 publications with CSPG4 and Muscle
 Brain Antibodies  >13 publications with CSPG4 and Brain
 Kidney Antibodies  >5 publications with CSPG4 and Kidney
 Liver Antibodies  >4 publications with CSPG4 and Liver
 Lung Antibodies  >4 publications with CSPG4 and Lung
 Intestine Antibodies  >4 publications with CSPG4 and Intestine
 Eye Antibodies  >2 publications with CSPG4 and Eye
 Placenta Antibodies  >2 publications with CSPG4 and Placenta
 Bone Antibodies  >2 publications with CSPG4 and Bone
 Blood Antibodies  >2 publications with CSPG4 and Blood
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