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VAV2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS476848

Entrez Summary: VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript… More details

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Product Overview

Product Name
VAV2, Monoclonal Antibody
Full Product Name
Anti-VAV2 Mouse mAb
Product Gene Name
Product Synonym Names
TKT; MIG20a; NTRKR3; TYRO10
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3B11E4
Host
Mouse
Species Reactivity
Human
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Molecular Weight
101.3
Immunogen
Purified recombinant fragment of human DDR2 expressed in E Coli.
Applications Tested/Suitable for anti-VAV2 antibody
Western Blot (WB), Flow Cytometry (FC/FACS)

Other Notes

Small volumes of anti-VAV2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VAV2 purchase

MBS476848 is an antibody targeting VAV2. Also known as Anti-VAV2 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for VAV2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Vav2
NCBI Official Synonym Full Names
vav 2 oncogene
NCBI Official Symbol
Vav2
NCBI Official Synonym Symbols
Vav-2; AI847175; 2810040F13Rik
UniProt Protein Name
Guanine nucleotide exchange factor VAV2
UniProt Gene Name
Vav2
UniProt Synonym Gene Names
VAV-2
NCBI Protein Information
guanine nucleotide exchange factor VAV2

NCBI Summary for VAV2

This gene encodes a member of the Vav family of Rho guanine nucleotide exchange factors. Vav family proteins are involved in the development and activation of lymphocytes, and the encoded protein may also be involved in angiogenesis. Disruption of this gene in mice is associated with heart, artery, and kidney defects, as well as tachycardia and hypertension. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
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UniProt Comments for VAV2

VAV2: a proto-oncogenic guanine nucleotide exchange factors (GEF) of the Dbl family. A GEF for the Rho family of GTP binding proteins. Expressed in most tissues.

Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2 A3|2 19.36 cM

Cellular Component: cytoplasm; plasma membrane

Molecular Function: epidermal growth factor receptor binding; guanyl-nucleotide exchange factor activity; protein binding

Biological Process: cell migration; cell projection biogenesis; lamellipodium biogenesis; positive regulation of phosphoinositide 3-kinase activity; regulation of blood coagulation; regulation of gene expression; regulation of GTPase activity; small GTPase mediated signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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