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Alpha Lactalbumin (LALBA) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS477237

MBS477237 is an antibody targeting LALBA. Also known as Lactose synthase B protein, Alpha-lactalbumin, Lactalbumin alpha, MGC138521. Reactive in Human. Host: Mouse. More details

$525 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
alpha Lactalbumin (LALBA), Monoclonal Antibody
Full Product Name
Lactose synthase B protein, Alpha-lactalbumin, Lactalbumin alpha, MGC138521
Product Gene Name
anti-LALBA antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10B3-6A7-7A8
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3
Purity/Purification
Affinity Purified
Preparation and Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
OMIM
149750
3D Structure
ModBase 3D Structure for P00709
Immunogen
Synthetic Peptide of alpha Lactalbumin
Target
The antibody detects endogenous alpha Lactalbumin proteins
Cellular localization
Secreted
Applications Tested/Suitable for anti-LALBA antibody
Western Blot (WB), Immunohistochemistry-Parafin (IHC-p), Immunohistocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-LALBA antibody
WB: 1:1000
IF: 1/200
IHC: 1/50-300

Western Blot (WB) of anti-LALBA antibody

Western blot analysis of 1) Human Milk, 2) Milk, with alpha Lactalbumin Mouse mAb diluted at 1:3, 000
Mouse Anti-LALBA Monoclonal Antibody – Cat# MBS477237

Immunofluorescence (IF) of anti-LALBA antibody

Immunofluorescence analysis of Human-breast tissue. 1,alpha Lactalbumin Monoclonal Antibody(9E9)(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B
Mouse Anti-LALBA Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS477237

Immunohistochemistry (IHC) of anti-LALBA antibody

Immunohistochemical analysis of paraffin-embedded Human-liver tissue. 1,alpha Lactalbumin Monoclonal Antibody(9E9) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.
Mouse Anti-LALBA Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS477237

Other Notes

Small volumes of anti-LALBA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LALBA. It may not necessarily be applicable to this product.

NCBI GI #
4504947
NCBI GeneID
3906
NCBI Accession #
NP_002280.1
UniProt Primary Accession #
P00709
UniProt Secondary Accession #
Q6FGX0; Q9UDK4
UniProt Related Accession #
P00709
GenBank Nucleotide #
NM_002289.2
NCBI Official Full Name
alpha-lactalbumin
NCBI Official Synonym Full Names
lactalbumin alpha
NCBI Official Symbol
LALBA
NCBI Official Synonym Symbols
LYZG
UniProt Protein Name
Alpha-lactalbumin
UniProt Synonym Protein Names
Lactose synthase B protein; Lysozyme-like protein 7
Protein Family
Alpha-lactalbumin
UniProt Gene Name
LALBA
UniProt Synonym Gene Names
LYZL7
NCBI Protein Information
alpha-lactalbumin

NCBI Summary for LALBA

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008]
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UniProt Comments for LALBA

Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
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Research Articles on LALBA

1. Studies indicate that alpha-lactalbumin has two domains, a large alpha-helical domain and a small beta-sheet domain connected by a calcium binding loop.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LALBA antibody

 Reference Product  PubMed Publications
 CSN2 antibody  >13 publications with LALBA and CSN2
 CSN3 antibody  >6 publications with LALBA and CSN3
 CSN1S1 antibody  >4 publications with LALBA and CSN1S1
 B4GALT1 antibody  >1 publications with LALBA and B4GALT1

Pathways associated with anti-LALBA antibody

 Products by Pathway  Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram

Diseases associated with anti-LALBA antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with LALBA and Inflammation
 Necrosis Antibodies  >1 publications with LALBA and Necrosis
 Cardiovascular Diseases Antibodies  >1 publications with LALBA and Cardiovascular Diseases
 Hyperplasia Antibodies  >1 publications with LALBA and Hyperplasia

Organs/Tissues associated with anti-LALBA antibody

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >1 publications with LALBA and Mixed
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