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Cytokeratin 18 (CYK 18) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS477242

MBS477242 is an antibody targeting CYK 18. Also known as Anti-Cytokeratin 18 Mouse mAb. Reactive in Human, Rat, Mouse. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Cytokeratin 18 (CYK 18), Monoclonal Antibody
Full Product Name
Anti-Cytokeratin 18 Mouse mAb
Product Gene Name
Product Synonym Names
Cell proliferation inducing gene 46 protein; CK 18; K 18; Keratin 18; Ketatin D; KRT18
Clonality
Monoclonal
Host
Mouse
Species Reactivity
Human, Rat, Mouse
Form/Format
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purity/Purification
Fractional precipitation
Preparation and Storage
Store at -20 degree C.
Molecular Weight
46
OMIM
148070
3D Structure
ModBase 3D Structure for P05783
Immunogen
Recombinant Protein
Applications Tested/Suitable for anti-CYK 18 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CYK 18 antibody
WB: 1:1,000-3000
ICC: 1:100-200
IHC: 1:200-500

Western Blot (WB) of anti-CYK 18 antibody

Western blot analysis of 1) HepG2, 2) Hela, 3) Mouse Liver tissue, 4) C2C12, 5) Rat Heart tissue, 6) Mouse Skeletal Muscle tissue with Cytokeratin 18 Mouse MAb (1B3) diluted at 1:2000.
Mouse Anti-CYK 18 Monoclonal Antibody – Cat# MBS477242

Immunofluorescence (IF) of anti-CYK 18 antibody

IF analysis of Hela with (Left) and DAPI (Right) diluted at 1:100.
Mouse Anti-CYK 18 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS477242

Immunohistochemistry (IHC) of anti-CYK 18 antibody

Immunohistochemical analysis of paraffin-embedded human breast caricnoma using Cytokeratin 18 uff08uff09Mouse mAb diluted at 1:500.
Mouse Anti-CYK 18 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS477242

Other Notes

Small volumes of anti-CYK 18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYK 18. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
keratin, type I cytoskeletal 18
NCBI Official Synonym Full Names
keratin 18
NCBI Official Symbol
KRT18
NCBI Official Synonym Symbols
K18; CK-18; CYK18
UniProt Protein Name
Keratin, type I cytoskeletal 18
UniProt Synonym Protein Names
Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
Protein Family
UniProt Gene Name
KRT18
UniProt Synonym Gene Names
CYK18; CK-18; K18
NCBI Protein Information
keratin, type I cytoskeletal 18

NCBI Summary for CYK 18

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for CYK 18

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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