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MRAP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS477665

MBS477665 is an antibody targeting MRAP2. Also known as Anti-MRAP2 (Center) Rabbit pAb. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MRAP2, Polyclonal Antibody
Full Product Name
Anti-MRAP2 (Center) Rabbit pAb
Product Gene Name
Product Synonym Names
Melanocortin-2 receptor accessory protein 2; MC2R accessory protein 2; MRAP2; C6orf117
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB32862
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied in PBS with 0.09% (W/V) sodium azide.
Purity/Purification
Purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
23,548 Da
OMIM
601665
3D Structure
ModBase 3D Structure for Q96G30
Immunogen
This MRAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human MRAP2.
Applications Tested/Suitable for anti-MRAP2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-MRAP2 antibody
WB: 1:1000
IHC: 1:10-50

Testing Data of anti-MRAP2 antibody

MRAP2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MRAP2 antibody detected the MRAP2 protein (arrow).
Rabbit Anti-MRAP2 Polyclonal Antibody – Cat# MBS477665

Immunohistochemistry (IHC) of anti-MRAP2 antibody

MRAP2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MRAP2 Antibody
Rabbit Anti-MRAP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS477665

Other Notes

Small volumes of anti-MRAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MRAP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
melanocortin-2 receptor accessory protein 2 isoform 2
NCBI Official Synonym Full Names
melanocortin 2 receptor accessory protein 2
NCBI Official Symbol
MRAP2
NCBI Official Synonym Symbols
C6orf117; bA51G5.2
UniProt Protein Name
Melanocortin-2 receptor accessory protein 2
UniProt Gene Name
MRAP2
UniProt Synonym Gene Names
C6orf117; MC2R accessory protein 2
NCBI Protein Information
melanocortin-2 receptor accessory protein 2

NCBI Summary for MRAP2

This gene encodes a protein that modulates melanocortin receptor signaling. The encoded protein has been shown to interact with all known melanocortin receptors and may regulate both receptor trafficking and activation in response to ligands. Mice lacking a functional copy of this gene exhibit severe obesity and a mutation in this gene may be associated with severe obesity in human patients. [provided by RefSeq, Oct 2016]
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UniProt Comments for MRAP2

Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP (). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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