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Beta I Tubulin (TUBB1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS477703

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). More details

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Product Overview

Product Name
beta I Tubulin (TUBB1), Polyclonal Antibody
Full Product Name
Anti-beta I Tubulin Rabbit pAb
Product Gene Name
anti-TUBB1 antibody
Product Synonym Names
Beta tubulin 1; class VI; Class VI beta tubulin antibody; TBB1_HUMAN; TUBB1; Tubulin beta 1 class VI; Tubulin; beta 1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Cow, Dog, Monkey
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity Chromatography
Specificity
beta I Tubulin Antibody detects endogenous levels of total beta I Tubulin
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Molecular Weight
50kDa
OMIM
612901
3D Structure
ModBase 3D Structure for Q9H4B7
Immunogen
A synthesized peptide derived from human beta I Tubulin
Subcellular Location
Cytoplasm; Cytoskeleton
Applications Tested/Suitable for anti-TUBB1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes for anti-TUBB1 antibody
WB: 1:3000-1:10000
IHC: 1:100-1:200
ICC/IF: 1:100-1:200
FC/FACS: 1:100

Western Blot (WB) of anti-TUBB1 antibody

Western blot analysis of beta I Tubulin expression in (1) K562 cell lysate; (2) Jurkat cell lysate; (3) HeLa cell lysate; (4) 293T cell lysate using beta I Tubulin antibody.
Rabbit Anti-TUBB1 Polyclonal Antibody – Cat# MBS477703

Immunohistochemistry (IHC) of anti-TUBB1 antibody

Immunohistochemical analysis of paraffin-embedded human tonsil, using beta I Tubulin Antibody.
Rabbit Anti-TUBB1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS477703

Immunofluorescence (IF) of anti-TUBB1 antibody

Immunofluorescent analysis of Hela cells, using beta I Tubulin Antibody.
Rabbit Anti-TUBB1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS477703

Other Notes

Small volumes of anti-TUBB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TUBB1 purchase

MBS477703 is an antibody targeting TUBB1. Also known as Anti-beta I Tubulin Rabbit pAb. Reactive in Human, Mouse, Rat, Cow, Dog, Monkey. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TUBB1. It may not necessarily be applicable to this product.

NCBI GI #
13562114
NCBI GeneID
81027
NCBI Accession #
NP_110400.1
UniProt Primary Accession #
Q9H4B7
UniProt Related Accession #
Q9H4B7
GenBank Nucleotide #
NM_030773.3
NCBI Official Full Name
tubulin beta-1 chain
NCBI Official Synonym Full Names
tubulin beta 1 class VI
NCBI Official Symbol
TUBB1
UniProt Protein Name
Tubulin beta-1 chain
Protein Family
Tubulin
UniProt Gene Name
TUBB1
NCBI Protein Information
tubulin beta-1 chain

NCBI Summary for TUBB1

This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010]
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UniProt Comments for TUBB1

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain ().

Research Articles on TUBB1

1. novel DCX mutation (p.D90G, NP_000546.2) appeared to be a major causative variant, whereas the novel mutation of TUBB1 (p.R62fsX, NP_110400.1) was found only in patients with more-severe intellectual disability in Familial pachygyria

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-TUBB1 antibody

 Products by Pathway  Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies  Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
 Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway antibodies  Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Orphan Transporters Pathway antibodies  Orphan Transporters Pathway Diagram
 Parkin-Ubiquitin Proteasomal System Pathway antibodies  Parkin-Ubiquitin Proteasomal System Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram

Diseases associated with anti-TUBB1 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3 publications with TUBB1 and Cardiovascular Diseases
 Immune System Diseases Antibodies  >3 publications with TUBB1 and Immune System Diseases
 Autoimmune Diseases Antibodies  >2 publications with TUBB1 and Autoimmune Diseases
 Lung Neoplasms Antibodies  >1 publications with TUBB1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >1 publications with TUBB1 and Breast Neoplasms
 Urinary Bladder Neoplasms Antibodies  >1 publications with TUBB1 and Urinary Bladder Neoplasms
 Macrothrombocytopenia, Autosomal Dominant, Tubb1-Related Antibodies  >1 publications with TUBB1 and Macrothrombocytopenia, Autosomal Dominant, Tubb1-Related
 Acute Coronary Syndrome Antibodies  >1 publications with TUBB1 and Acute Coronary Syndrome

Organs/Tissues associated with anti-TUBB1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >11 publications with TUBB1 and Blood
 Lung Antibodies  >1 publications with TUBB1 and Lung
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