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PTBP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS477791

RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing,… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
PTBP2, Polyclonal Antibody
Full Product Name
Anti-PTBP2 Rabbit pAb
Product Gene Name
Product Synonym Names
brPTB; MIBP; nPTB; Polypyrimidine tract binding protein 2; PTB like protein; PTBP 2Ptbp2; Splicing regulator
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity Chromatography
Specificity
PTBP2 Antibody detects endogenous levels of total PTBP2
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Molecular Weight
57kDa
OMIM
608449
3D Structure
ModBase 3D Structure for Q9UKA9
Immunogen
A synthesized peptide derived from human PTBP2
Subcellular Location
Nucleus
Applications Tested/Suitable for anti-PTBP2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-PTBP2 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

Western Blot (WB) of anti-PTBP2 antibody

Western blot analysis of PTBP2 in (1) Neuro-2a cell lysate; (2) HeLa cell lysate.
Rabbit Anti-PTBP2 Polyclonal Antibody – Cat# MBS477791

Immunohistochemistry (IHC) of anti-PTBP2 antibody

Immunohistochemical analysis of paraffin-embedded human colon, using PTBP2 Antibody.
Rabbit Anti-PTBP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS477791

Other Notes

Small volumes of anti-PTBP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTBP2 purchase

MBS477791 is an antibody targeting PTBP2. Also known as Anti-PTBP2 Rabbit pAb. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PTBP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
polypyrimidine tract-binding protein 2 isoform 1
NCBI Official Synonym Full Names
polypyrimidine tract binding protein 2
NCBI Official Symbol
PTBP2
NCBI Official Synonym Symbols
nPTB; PTBLP; brPTB
UniProt Protein Name
Polypyrimidine tract-binding protein 2
UniProt Synonym Protein Names
Neural polypyrimidine tract-binding protein; Neurally-enriched homolog of PTB; PTB-like protein
UniProt Gene Name
PTBP2
UniProt Synonym Gene Names
NPTB; PTB; PTBLP
NCBI Protein Information
polypyrimidine tract-binding protein 2

NCBI Summary for PTBP2

The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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