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Cytokeratin 19 (CK19) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS477842

Cytokeratin 19, also known as KRT19, CK19, CK19, K1CS, MGC15366. Entrez Protein NP_002267. It is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided… More details

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Product Overview

Product Name
Cytokeratin 19 (CK19), Polyclonal Antibody
Full Product Name
Anti-Cytokeratin 19 Rabbit pAb
Product Gene Name
Product Synonym Names
KRT19; K1CS; K19; CK 19; Cytokeratin 19; MGC15366
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity Chromatography
Specificity
Cytokeratin 19 Antibody detects endogenous levels of total Cytokeratin 19
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Molecular Weight
40kDa
OMIM
148020
3D Structure
ModBase 3D Structure for P08727
Immunogen
A synthesized peptide derived from human Cytokeratin 19
Subcellular Location
Cytoplasm; Cytoskeleton; Spindle Pole
Applications Tested/Suitable for anti-CK19 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes for anti-CK19 antibody
WB: 1:5000-1:10000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
FC/FACS: 1:50

Western Blot (WB) of anti-CK19 antibody

Western blot analysis of Cytokeratin 19 expression in HepG2 cell lysate.
Rabbit Anti-CK19 Polyclonal Antibody – Cat# MBS477842

Immunohistochemistry (IHC) of anti-CK19 antibody

Immunohistochemical analysis of paraffin-embedded mouse colon, using Cytokeratin 19 Antibody.
Rabbit Anti-CK19 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS477842

Immunofluorescence (IF) of anti-CK19 antibody

Immunofluorescent analysis of MCF-7 cells, using Cytokeratin 19 Antibody.
Rabbit Anti-CK19 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS477842

Other Notes

Small volumes of anti-CK19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CK19 purchase

MBS477842 is an antibody targeting CK19. Also known as Anti-Cytokeratin 19 Rabbit pAb. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CK19. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
keratin, type I cytoskeletal 19
NCBI Official Synonym Full Names
keratin 19
NCBI Official Symbol
KRT19
NCBI Official Synonym Symbols
K19; CK19; K1CS
UniProt Protein Name
Keratin, type I cytoskeletal 19
UniProt Synonym Protein Names
Cytokeratin-19; CK-19; Keratin-19; K19
Protein Family
UniProt Gene Name
KRT19
UniProt Synonym Gene Names
CK-19; K19
NCBI Protein Information
keratin, type I cytoskeletal 19

NCBI Summary for CK19

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
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UniProt Comments for CK19

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CK19 antibody

Pathways associated with anti-CK19 antibody

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