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Pi 3 Kinase Class 3 (PIK3C3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS477851

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PI 3 Kinase Class 3 (PIK3C3), Polyclonal Antibody
Full Product Name
Anti-PI 3 Kinase Class 3 Rabbit pAb
Product Gene Name
Product Synonym Names
Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC:2.7.1.137); PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity Chromatography
Specificity
PI 3 Kinase Class 3 Antibody detects endogenous levels of total PI 3 Kinase Class 3
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Molecular Weight
100kDa
OMIM
602609
3D Structure
ModBase 3D Structure for Q8NEB9
Immunogen
A synthesized peptide derived from human PI 3 Kinase Class 3
Subcellular Location
Nucleus
Applications Tested/Suitable for anti-PIK3C3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PIK3C3 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-PIK3C3 antibody

Western blot analysis of PI 3 Kinase Class 3 expression in 293T cell lysate.
Rabbit Anti-PIK3C3 Polyclonal Antibody – Cat# MBS477851

Immunohistochemistry (IHC) of anti-PIK3C3 antibody

Immunohistochemical analysis of paraffin-embedded human kidney, using PI 3 Kinase Class 3 Antibody.
Rabbit Anti-PIK3C3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS477851

Other Notes

Small volumes of anti-PIK3C3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PIK3C3 purchase

MBS477851 is an antibody targeting PIK3C3. Also known as Anti-PI 3 Kinase Class 3 Rabbit pAb. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PIK3C3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1
NCBI Official Synonym Full Names
phosphatidylinositol 3-kinase catalytic subunit type 3
NCBI Official Symbol
PIK3C3
NCBI Official Synonym Symbols
VPS34; Vps34; hVps34
UniProt Protein Name
Phosphatidylinositol 3-kinase catalytic subunit type 3
UniProt Synonym Protein Names
Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34
UniProt Gene Name
PIK3C3
UniProt Synonym Gene Names
PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3
NCBI Protein Information
phosphatidylinositol 3-kinase catalytic subunit type 3

UniProt Comments for PIK3C3

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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