GST M2-2 Recombinant Protein

Name: GST M2-2 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS480637
Price: 695 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS480637

MBS480637 is a recombinant protein targeting GST M2-2. Also known as GST M2-2, Recombinant Human. Host: Human recombinant protein expressed in E Coli. More details

$695 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GST M2-2, Recombinant Protein

Full Product Name

GST M2-2, Recombinant Human

Product Gene Name

GST M2-2 recombinant protein

Product Synonym Names

Recombinant Human GST M2-2

Host

Human recombinant protein expressed in E Coli.

Purity/Purification

95% as assessed by inspection on a Coomassie Blue-stained SDS-PAGE gel.

Concentration

2.55 mg/mL total protein using the Bradford protein assay with BSA as a standard. (lot specific)

Specificity

Specific Activity: 93.3 Units/mg using spectrophotometric determination of 1- chloro-2,4-dinitrobenzene (CDNB) conjugation with reduced glutathione (1 mM) in 100 mM NaPO4 (pH 6.5) at room temperature.

Preparation and Storage

At -20 degree C; AVOID MULTIPLE FREEZE-THAW CYCLES.

Molecular Weight

26 kDa

3D Structure

ModBase 3D Structure for P15626

Storage Buffer

50 mM Tris-HCl (pH 7.5), 50 mM NaCl, 1 mM DTT, 1 mM EDTA and 50% glycerol.

Procedural Notes

This purified product exhibits high enzymatic activity for CDNB, the synthetic substrate that is most commonly used for GST analyses. However, as is widely known for GST activity analysis using CDNB as a substrate, low concentrations (high dilutions) of the enzyme result in lower activity values. In contrast, initial velocities are much higher for more concentrated levels of enzyme but the rate decreases rapidly. Therefore, activity toward CDNB and these considerations provide guidance when assaying this product under low concentrations or when using substrates other than CDNB.

Other Notes

Small volumes of GST M2-2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GST M2-2. It may not necessarily be applicable to this product.

NCBI GI #

6680121

NCBI GeneID

14863

NCBI Accession #

NP_032209.1

UniProt Primary Accession #

P15626

UniProt Related Accession #

P15626

GenBank Nucleotide #

NM_008183.3

NCBI Official Full Name

glutathione S-transferase Mu 2

NCBI Official Synonym Full Names

glutathione S-transferase, mu 2

NCBI Official Symbol

Gstm2

NCBI Official Synonym Symbols

Gstb2; Gstb-2

UniProt Protein Name

Glutathione S-transferase Mu 2

UniProt Synonym Protein Names

GST 5-5; GST class-mu 2; Glutathione S-transferase pmGT2

UniProt Gene Name

Gstm2

UniProt Entry Name

GSTM2_MOUSE

NCBI Protein Information

glutathione S-transferase Mu 2; GST 5-5; GST class-mu 2; glutathione S-transferase pmGT2; glutathione-S-transferase, mu 2

UniProt Comments for GST M2-2

GSTM5: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Mu family.

Protein type: EC 2.5.1.18; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Other Amino Acids Metabolism - glutathione; Transferase

Cellular Component: protein complex; cytoplasm; plasma membrane; cytosol

Molecular Function: transferase activity; enzyme binding; protein homodimerization activity; glutathione binding; glutathione transferase activity; protein heterodimerization activity

Biological Process: glutathione metabolic process; nitrobenzene metabolic process; metabolic process; xenobiotic catabolic process

Research Articles on GST M2-2

1. Gstm2 is highly expressed in the uterine luminal epithelium during preimplantation period and up-regulated by progesterone.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GST M2-2 recombinant protein

Reference Product	PubMed Publications
Gstm1 recombinant protein	>34 publications with GST M2-2 and Gstm1
Gstm3 recombinant protein	>26 publications with GST M2-2 and Gstm3
Gstt2 recombinant protein	>11 publications with GST M2-2 and Gstt2
Gsto1 recombinant protein	>10 publications with GST M2-2 and Gsto1
Gstt1 recombinant protein	>7 publications with GST M2-2 and Gstt1
Cyp1a2 recombinant protein	>5 publications with GST M2-2 and Cyp1a2
Cyp1a1 recombinant protein	>4 publications with GST M2-2 and Cyp1a1
Cyp2e1 recombinant protein	>3 publications with GST M2-2 and Cyp2e1
Ephx1 recombinant protein	>1 publications with GST M2-2 and Ephx1

Pathways associated with GST M2-2 recombinant protein

Products by Pathway	Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Chemical Carcinogenesis Pathway antibodies	Chemical Carcinogenesis Pathway Diagram
Chemical Carcinogenesis Pathway antibodies	Chemical Carcinogenesis Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Glutathione Conjugation Pathway antibodies	Glutathione Conjugation Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Glutathione Metabolism Pathway antibodies	Glutathione Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram

Diseases associated with GST M2-2 recombinant protein

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>10 publications with GST M2-2 and Liver Diseases
Liver Neoplasms Antibodies	>6 publications with GST M2-2 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>5 publications with GST M2-2 and Carcinoma, Hepatocellular
Breast Neoplasms Antibodies	>4 publications with GST M2-2 and Breast Neoplasms
Neoplasms, Experimental Antibodies	>4 publications with GST M2-2 and Neoplasms, Experimental
Cardiovascular Diseases Antibodies	>4 publications with GST M2-2 and Cardiovascular Diseases
Hypertension Antibodies	>4 publications with GST M2-2 and Hypertension
Liver Neoplasms, Experimental Antibodies	>3 publications with GST M2-2 and Liver Neoplasms, Experimental
Disease Models, Animal Antibodies	>3 publications with GST M2-2 and Disease Models, Animal
Precancerous Conditions Antibodies	>3 publications with GST M2-2 and Precancerous Conditions

Organs/Tissues associated with GST M2-2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>24 publications with GST M2-2 and Liver
Blood Antibodies	>16 publications with GST M2-2 and Blood
Muscle Antibodies	>11 publications with GST M2-2 and Muscle
Heart Antibodies	>10 publications with GST M2-2 and Heart
Lung Antibodies	>9 publications with GST M2-2 and Lung
Kidney Antibodies	>8 publications with GST M2-2 and Kidney
Brain Antibodies	>7 publications with GST M2-2 and Brain
Ovary Antibodies	>4 publications with GST M2-2 and Ovary
Intestine Antibodies	>4 publications with GST M2-2 and Intestine
Testis Antibodies	>4 publications with GST M2-2 and Testis