UGT-Express 2b7 (UGT) Enzyme

UGT-Express is a catalytic system with individual native human UGTs (UDP-glucuronosyltransferase) co-expressed with UDP-glucose dehydrogenase. This system shows high catalytic activity and reduces costs as it does not require the addition of UGT-glucuronic acid.

Advantages of the Express Technology
Stability: Our dry powder preparations have enhanced thermal stability permitting storage in a refrigerator or even at room temperature prior to use.
Significantly lower cost: Lower cost for the UGT — and UDP-glucuronic acid is generated in situ
More natural: Native human enzyme sequence in a Eukaryotic lipid milieu.
Semipermeable encapsulation: This format allows us to co-express ancillary enzymes to make expensive cofactors and co-substrates, thereby further reducing costs.
Enhanced solvent stability: Many drug candidates are poorly soluble in water and require use of an organic solvent. Express enzymes tolerate higher concentrations of organic solvents.
Ease of use: Just weigh out, add buffer, substrate and UDP-glucose

Small volumes of UGT enzyme vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS480877 is an enzyme targeting UGT. Also known as UGT-Express 2B7.